Shetty Sudarshan A, Ritari Jarmo, Paulin Lars, Smidt Hauke, De Vos Willem M
Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands.
Department of Veterinary Biosciences, Division of Microbiology and Epidemiology, University of Helsinki, Helsinki, Finland.
Genome Announc. 2017 Oct 26;5(43):e01167-17. doi: 10.1128/genomeA.01167-17.
The complete genome sequence of strain L2-7 is reported here. This intestinal strain produces butyrate from glucose as well as lactate when acetate is provided in the growth medium. In addition, strain L2-7 has been shown to improve insulin sensitivity in db/db mice, indicating its application potential.
本文报道了菌株L2-7的完整基因组序列。该肠道菌株在生长培养基中提供乙酸盐时,能利用葡萄糖以及乳酸产生丁酸盐。此外,菌株L2-7已被证明可改善db/db小鼠的胰岛素敏感性,表明其具有应用潜力。