School of Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China; Key Laboratory of Vision Science, Ministry of Health P.R. China, Wenzhou, Zhejiang, China.
School of Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
J Cataract Refract Surg. 2019 Mar;45(3):298-304. doi: 10.1016/j.jcrs.2018.10.033.
To assess the repeatability and agreement of anterior segment measurements between an optical biometer (IOLMaster 700) using swept-source optical coherence tomography and a Scheimpflug-Placido tomographer (Sirius) in patients scheduled for corneal refractive surgery.
Eye Hospital of Wenzhou Medical University, Zhejiang, China.
Prospective case series.
The parameters, including the central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, keratometry (K) values, astigmatism, J0 (Jackson cross-cylinder with axes at 180 degree and 90 degrees) and J45 vectors (Jackson cross-cylinder with axes at 45 degrees and 135 degrees), and horizontal corneal diameter, were measured 3 times per instrument. The intraobserver repeatability was assessed using test-retest repeatability, the coefficient of variation (CoV), and the intraclass correlation coefficient (ICC). Paired t tests were used to compare the difference between the 2 methods. Agreement was evaluated using Bland-Altman analyses.
The study enrolled 100 right eyes. All measurements of the 2 devices showed high repeatability. The CoV of all measured parameters was less than 0.93 and the ICC value was more than 0.85. The paired t test did not show a significant difference in CCT, astigmatism, J0 or J45 vector. The mean ACD and aqueous depth were statistically lower with the optical biometer; however, the 95% limits of agreement (LoA) were low (from -0.20 to -0.03 mm). The K and corneal diameter values obtained using the optical biometer were higher by 0.1 diopter and 0.1 mm, respectively, but with narrow 95% LoA.
The optical biometer and the Scheimpflug-Placido tomographer showed high repeatability for all anterior segment measurements. The measured parameters showed good agreement and could be used interchangeably.
评估在计划行角膜屈光手术的患者中，使用扫频源光相干断层扫描仪（IOLMaster 700）的眼前节测量与Scheimpflug-Placido 断层扫描仪（Sirius）之间的重复性和一致性。
中国浙江温州医科大学附属眼视光医院。
前瞻性病例系列。
测量参数包括中央角膜厚度（CCT）、前房深度（ACD）、房水深度、角膜曲率（K）值、散光、J0（Jackson 交叉圆柱镜，轴在 180 度和 90 度）和 J45 矢量（Jackson 交叉圆柱镜，轴在 45 度和 135 度）以及水平角膜直径，每种仪器测量 3 次。使用测试-再测试重复性、变异系数（CoV）和组内相关系数（ICC）评估观察者内重复性。使用配对 t 检验比较两种方法之间的差异。使用 Bland-Altman 分析评估一致性。
本研究纳入 100 只右眼。两种设备的所有测量值均具有高度的可重复性。所有测量参数的 CoV 均小于 0.93，ICC 值均大于 0.85。配对 t 检验显示 CCT、散光、J0 或 J45 矢量无显著差异。光学生物测量仪测量的平均 ACD 和房水深度较低，但 95%的一致性范围（LoA）较低（从-0.20 到-0.03mm）。光学生物测量仪测量的 K 值和角膜直径分别高 0.1 屈光度和 0.1mm，但 95%LoA 较窄。
光学生物测量仪和 Scheimpflug-Placido 断层扫描仪对所有眼前节测量均具有高度的重复性。所测量的参数具有良好的一致性，可以互换使用。
