• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

不同类型乳制品的摄入与荷兰老年人认知表现的关系:B-PROOF 研究。

Associations between the Intake of Different Types of Dairy and Cognitive Performance in Dutch Older Adults: The B-PROOF Study.

机构信息

Division of Human Nutrition and Health, Wageningen University & Research, 6708WE Wageningen, The Netherlands.

出版信息

Nutrients. 2020 Feb 13;12(2):468. doi: 10.3390/nu12020468.

DOI:10.3390/nu12020468
PMID:32069791
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7071379/
Abstract

Various dairy nutrients have been associated with cognitive performance. Several observational studies have explored associations between the intake of total dairy or some dairy subgroups and cognitive performance. However, studies on the potential impact of a broad variety of dairy subclasses are scarce. We examined cross-sectional associations between a wide assortment of dairy products and cognitive performance. A total of 619 Dutch community-dwelling adults aged ≥65 years completed a semi-quantitative Food Frequency Questionnaire. Cognitive performance was assessed with an extensive neuropsychological test battery; the tests were clustered into cognitive domains using z-scores. Linear and logistic regression analyses, adjusted for age, sex, BMI, education, smoking, alcohol consumption, habitual physical activity, total energy intake, and dietary factors, were performed to quantify the associations. The Benjamini-Hochberg method was used to correct for multiple testing. After full adjustment, higher skimmed dairy (β ± SD: 0.05 ± 0.02, = 0.06), fermented dairy (0.04 ± 0.02, = 0.09), and buttermilk (0.08 ± 0.03, = 0.19) consumption were associated with better executive functioning. Logistic regression analyses indicated that a 30 g increase in Dutch cheese intake was associated with a 33% lower probability of poor information processing speed (PR = 0.67, 95% CI 0.47-0.97). No associations were observed between dairy consumption and attention and working memory or episodic memory.

摘要

各种乳制品营养成分与认知表现有关。一些观察性研究探讨了总乳制品或某些乳制品亚组的摄入量与认知表现之间的关系。然而,关于广泛的乳制品亚类对认知表现的潜在影响的研究却很少。我们研究了各种乳制品与认知表现之间的横断面关联。共有 619 名年龄≥65 岁的荷兰社区居住成年人完成了半定量食物频率问卷。认知表现通过广泛的神经心理学测试进行评估;使用 z 分数将测试聚类为认知域。进行线性和逻辑回归分析,调整年龄、性别、BMI、教育、吸烟、饮酒、习惯性体力活动、总能量摄入和饮食因素,以量化关联。使用 Benjamini-Hochberg 方法进行多重检验校正。在充分调整后,较高的脱脂乳制品(β ± SD:0.05 ± 0.02, = 0.06)、发酵乳制品(0.04 ± 0.02, = 0.09)和酪乳(0.08 ± 0.03, = 0.19)的摄入量与更好的执行功能有关。逻辑回归分析表明,荷兰奶酪摄入量增加 30 克与信息处理速度较差的概率降低 33%(PR = 0.67,95%CI 0.47-0.97)有关。乳制品摄入量与注意力和工作记忆或情景记忆之间没有关联。

相似文献

1
Associations between the Intake of Different Types of Dairy and Cognitive Performance in Dutch Older Adults: The B-PROOF Study.不同类型乳制品的摄入与荷兰老年人认知表现的关系:B-PROOF 研究。
Nutrients. 2020 Feb 13;12(2):468. doi: 10.3390/nu12020468.
2
Dairy shows different associations with abdominal and BMI-defined overweight: Cross-sectional analyses exploring a variety of dairy products.乳制品与腹部超重和体重指数定义的超重呈现不同的关联:探索多种乳制品的横断面分析。
Nutr Metab Cardiovasc Dis. 2018 May;28(5):451-460. doi: 10.1016/j.numecd.2018.01.008. Epub 2018 Mar 30.
3
Milk, Yogurt, and Cheese Intake Is Positively Associated With Cognitive Executive Functions in Older Adults of the Canadian Longitudinal Study on Aging.牛奶、酸奶和奶酪的摄入量与加拿大老龄化纵向研究中老年人的认知执行功能呈正相关。
J Gerontol A Biol Sci Med Sci. 2021 Nov 15;76(12):2223-2231. doi: 10.1093/gerona/glab165.
4
Higher Mediterranean Diet scores are not cross-sectionally associated with better cognitive scores in 20- to 70-year-old Dutch adults: The NQplus study.高地中海饮食评分与 20 至 70 岁荷兰成年人的更好认知评分并无横断面关联:NQplus 研究。
Nutr Res. 2018 Nov;59:80-89. doi: 10.1016/j.nutres.2018.07.013. Epub 2018 Jul 29.
5
Consumption of Dairy Products and Cognitive Functioning: Findings from the SU.VI.MAX 2 Study.乳制品消费与认知功能:SU.VI.MAX 2研究的结果
J Nutr Health Aging. 2016 Feb;20(2):128-37. doi: 10.1007/s12603-015-0593-x.
6
Dairy intake and cognitive health in middle-aged South Australians.南澳大利亚中年人的乳制品摄入量与认知健康
Asia Pac J Clin Nutr. 2010;19(2):161-71.
7
Dairy product consumption is associated with pre-diabetes and newly diagnosed type 2 diabetes in the Lifelines Cohort Study.乳制品消费与 Lifelines 队列研究中的前驱糖尿病和新诊断的 2 型糖尿病有关。
Br J Nutr. 2018 Feb;119(4):442-455. doi: 10.1017/S0007114517003762.
8
Baseline Association of Motoric Cognitive Risk Syndrome With Sustained Attention, Memory, and Global Cognition.运动认知风险综合征与持续性注意力、记忆力和整体认知的基线关联。
J Am Med Dir Assoc. 2018 Jan;19(1):53-58. doi: 10.1016/j.jamda.2017.07.016. Epub 2017 Sep 9.
9
Intake of different types of dairy and its prospective association with risk of type 2 diabetes: The Rotterdam Study.不同类型乳制品的摄入量及其与2型糖尿病风险的前瞻性关联:鹿特丹研究
Nutr Metab Cardiovasc Dis. 2016 Nov;26(11):987-995. doi: 10.1016/j.numecd.2016.08.003. Epub 2016 Aug 10.
10
Dairy intake is associated with memory and pulsatility index in heart failure.乳制品摄入量与心力衰竭中的记忆力和搏动指数相关。
Int J Neurosci. 2015 Apr;125(4):247-52. doi: 10.3109/00207454.2014.928290. Epub 2014 Jun 27.

引用本文的文献

1
Milk free of A1 β-casein supports superior gains in cognition and quality of life, relative to conventional milk, in older adults with mild cognitive impairment.对于患有轻度认知障碍的老年人,不含A1 β-酪蛋白的牛奶相对于传统牛奶,能在认知和生活质量方面带来更显著的提升。
J Nutr Health Aging. 2025 May 14;29(7):100579. doi: 10.1016/j.jnha.2025.100579.
2
Fermented Dairy Products, Musculoskeletal and Mental Health in Older Adults: is There Evidence to Support Benefits that go Beyond Those of Non-Fermented Dairy Products?发酵乳制品、老年人的肌肉骨骼和心理健康:是否有证据支持其益处超越非发酵乳制品?
Calcif Tissue Int. 2024 Nov;115(5):480-497. doi: 10.1007/s00223-024-01291-4. Epub 2024 Sep 20.
3
Association between the Intake/Type of Cheese and Cognitive Function in Community-Dwelling Older Women in Japan: A Cross-Sectional Cohort Study.日本社区居住的老年女性中奶酪摄入量/类型与认知功能的关系:一项横断面队列研究。
Nutrients. 2024 Aug 22;16(16):2800. doi: 10.3390/nu16162800.
4
Effectiveness of dairy products to protect against cognitive decline in later life: a narrative review.乳制品预防晚年认知衰退的有效性:一项叙述性综述。
Front Nutr. 2024 Jun 19;11:1366949. doi: 10.3389/fnut.2024.1366949. eCollection 2024.
5
Consumption of Olive Oil and Diet Quality and Risk of Dementia-Related Death.橄榄油的摄入与饮食质量和与痴呆相关的死亡风险。
JAMA Netw Open. 2024 May 1;7(5):e2410021. doi: 10.1001/jamanetworkopen.2024.10021.
6
Energy intake, hydration status, and sleep of world-class male archers during competition.世界级男射箭运动员比赛期间的能量摄入、水合状态和睡眠。
J Int Soc Sports Nutr. 2024 Dec;21(1):2345358. doi: 10.1080/15502783.2024.2345358. Epub 2024 May 6.
7
Role of fermented dairy products in the health benefits of a mediterranean diet.发酵乳制品在地中海饮食健康益处中的作用。
Aging Clin Exp Res. 2024 Mar 19;36(1):75. doi: 10.1007/s40520-024-02721-x.
8
Alzheimer's Disease Genetic Influences Impact the Associations between Diet and Resting-State Functional Connectivity: A Study from the UK Biobank.阿尔茨海默病的遗传影响会影响饮食与静息态功能连接之间的关联:来自英国生物银行的一项研究。
Nutrients. 2023 Jul 30;15(15):3390. doi: 10.3390/nu15153390.
9
Inverse Association between Cheese Consumption and Lower Cognitive Function in Japanese Community-Dwelling Older Adults Based on a Cross-Sectional Study.基于一项横断面研究,日本社区居住的老年人群中奶酪摄入与较低认知功能呈负相关。
Nutrients. 2023 Jul 18;15(14):3181. doi: 10.3390/nu15143181.
10
Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies.奶酪消费与多种健康结局:前瞻性研究的伞式综述和更新的荟萃分析。
Adv Nutr. 2023 Sep;14(5):1170-1186. doi: 10.1016/j.advnut.2023.06.007. Epub 2023 Jun 15.

本文引用的文献

1
Menaquinone Content of Cheese.奶酪中的甲萘醌含量。
Nutrients. 2018 Apr 4;10(4):446. doi: 10.3390/nu10040446.
2
Lactobacillus helveticus-fermented milk containing lactononadecapeptide (NIPPLTQTPVVVPPFLQPE) improves cognitive function in healthy middle-aged adults: a randomised, double-blind, placebo-controlled trial.含乳双歧杆菌发酵乳的乳酮六肽(NIPPLTQTPVVVPPFLQPE)可改善健康中年成年人的认知功能:一项随机、双盲、安慰剂对照试验。
Int J Food Sci Nutr. 2018 May;69(3):369-376. doi: 10.1080/09637486.2017.1365824. Epub 2017 Aug 18.
3
Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer's Disease: A Randomized, Double-Blind and Controlled Trial.补充益生菌对阿尔茨海默病认知功能和代谢状态的影响:一项随机、双盲和对照试验
Front Aging Neurosci. 2016 Nov 10;8:256. doi: 10.3389/fnagi.2016.00256. eCollection 2016.
4
Consumption of Dairy Products and Cognitive Functioning: Findings from the SU.VI.MAX 2 Study.乳制品消费与认知功能:SU.VI.MAX 2研究的结果
J Nutr Health Aging. 2016 Feb;20(2):128-37. doi: 10.1007/s12603-015-0593-x.
5
Cognitive Performance: A Cross-Sectional Study on Serum Vitamin D and Its Interplay With Glucose Homeostasis in Dutch Older Adults.认知表现:一项关于荷兰老年人血清维生素D及其与葡萄糖稳态相互作用的横断面研究。
J Am Med Dir Assoc. 2015 Jul 1;16(7):621-7. doi: 10.1016/j.jamda.2015.02.013. Epub 2015 Mar 30.
6
Comparison of methods to account for implausible reporting of energy intake in epidemiologic studies.流行病学研究中能量摄入不合理报告的处理方法比较。
Am J Epidemiol. 2015 Feb 15;181(4):225-33. doi: 10.1093/aje/kwu308. Epub 2015 Feb 5.
7
Relation between dairy food intake and cognitive function: The Maine-Syracuse Longitudinal Study.乳制品摄入量与认知功能之间的关系:缅因州-锡拉丘兹纵向研究
Int Dairy J. 2012 Jan 1;22(1):15-23. doi: 10.1016/j.idairyj.2011.08.001.
8
Relative validity of the food frequency questionnaire used to assess dietary intake in the Leiden Longevity Study.用于评估莱顿长寿研究中饮食摄入的食物频率问卷的相对有效性。
Nutr J. 2013 Jun 7;12:75. doi: 10.1186/1475-2891-12-75.
9
Consumption of fermented milk product with probiotic modulates brain activity.食用含有益生菌的发酵乳制品可调节大脑活动。
Gastroenterology. 2013 Jun;144(7):1394-401, 1401.e1-4. doi: 10.1053/j.gastro.2013.02.043. Epub 2013 Mar 6.
10
Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation.益生菌对肠道微生物群的影响:肠道免疫调节和神经调节的机制。
Therap Adv Gastroenterol. 2013 Jan;6(1):39-51. doi: 10.1177/1756283X12459294.