Laboratory of Biological Modeling, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.
J Neurophysiol. 2020 May 1;123(5):1645-1656. doi: 10.1152/jn.00404.2019. Epub 2020 Mar 18.
The Wilson-Cowan equations represent a landmark in the history of computational neuroscience. Along with the insights Wilson and Cowan offered for neuroscience, they crystallized an approach to modeling neural dynamics and brain function. Although their iconic equations are used in various guises today, the ideas that led to their formulation and the relationship to other approaches are not well known. Here, we give a little context to some of the biological and theoretical concepts that lead to the Wilson-Cowan equations and discuss how to extend beyond them.
威尔逊-考恩方程代表了计算神经科学史上的一个里程碑。威尔逊和考恩为神经科学提供的见解,以及他们提出的建模神经动力学和大脑功能的方法,都具有重要意义。尽管如今这些标志性的方程以各种形式被使用,但导致它们被提出的思想以及与其他方法的关系却鲜为人知。在这里,我们将为威尔逊-考恩方程的一些生物学和理论概念提供一些背景,并讨论如何在此基础上进行扩展。