Han Peipei, Zhang Xuping, Xu Dan, Zhang Bowen, Lai Daowan, Zhou Ligang
Department of Plant Pathology, College of Plant Protection, China Agricultural University, Beijing 100193, China.
J Fungi (Basel). 2020 Oct 16;6(4):229. doi: 10.3390/jof6040229.
(teleomorph: ) fungi are well known to produce a variety of secondary metabolites with various biological activities to show their pharmaceutical and agrochemical applications. Up to now, at least 229 secondary metabolites, mainly including 84 nitrogen-containing metabolites, 85 polyketides, 40 terpenoids, and 20 other metabolites, have been reported. Many of these compounds exhibit biological activities, such as cytotoxic, antimicrobial, antileishmanial, antimalarial activities. This mini-review aims to summarize the diversity of the secondary metabolites as well as their occurrences in fungi and biological activities.
(有性型:)众所周知,真菌会产生多种具有不同生物活性的次生代谢产物,以展现其在制药和农用化学品方面的应用。截至目前,已报道了至少229种次生代谢产物,主要包括84种含氮代谢产物、85种聚酮化合物、40种萜类化合物和20种其他代谢产物。这些化合物中的许多都具有生物活性,如细胞毒性、抗菌、抗利什曼原虫、抗疟活性。本综述旨在总结次生代谢产物的多样性及其在真菌中的存在情况和生物活性。