Department of Pharmacy, Jagannath University, Sadarghat, Dhaka-1100, Bangladesh.
Department of Pharmacy, Southeast University, Banani, Dhaka-1213, Bangladesh.
Environ Sci Pollut Res Int. 2021 Dec;28(48):68071-68089. doi: 10.1007/s11356-021-16809-8. Epub 2021 Oct 18.
In the light of thousands of infections and deaths, the World Health Organization (WHO) has declared the outbreak of coronavirus disease (COVID-19) a worldwide pandemic. It has spread to about 22 million people worldwide, with a total of 0.45 million expiries, limiting the movement of most people worldwide in the last 6 months. However, COVID-19 became the foremost health, economic, and humanitarian challenge of the twenty-first century. Measures intended to curb the pandemic of COVID-19 included travel bans, lockdowns, and social distances through shelter orders, which will further stop human activities suddenly and eventually impact the world and the national economy. The viral disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). After SARS-CoV-2 virus and Middle East respiratory syndrome (MERS)-related CoV, COVID-19 is the third most significant lethal disease to humans. According to WHO, COVID-19 mortality exceeded that of SARS and MERS since COVID-19 was declared an international public health emergency. Genetic sequencing has recently established that COVID-19 is close to SARS-CoV and bat coronavirus which has not yet been recognized as the key cause of this pandemic outbreak, its transmission, and human pathogen mechanism. This review focuses on a brief introduction of novel coronavirus pathogens, including coronavirus in humans and animals, its taxonomic classification, symptoms, pathogenicity, social impact, economic impact, and potential treatment therapy for COVID-19.
在数千例感染和死亡病例的背景下,世界卫生组织(WHO)宣布冠状病毒病(COVID-19)爆发为全球大流行。它已传播到全球约 2200 万人,总共有 45 万人死亡,限制了过去 6 个月内全球大多数人的行动。然而,COVID-19 成为 21 世纪首要的健康、经济和人道主义挑战。旨在遏制 COVID-19 大流行的措施包括旅行禁令、封锁和通过庇护令实施社交距离,这将突然停止人类活动,并最终影响世界和国家经济。这种病毒性疾病是由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的。在 SARS-CoV-2 病毒和中东呼吸综合征(MERS)相关 CoV 之后,COVID-19 是对人类第三致命的疾病。根据世界卫生组织的数据,自 COVID-19 被宣布为国际公共卫生紧急事件以来,COVID-19 的死亡率超过了 SARS 和 MERS。遗传测序最近证实,COVID-19 与 SARS-CoV 和尚未被认为是这种大流行爆发、其传播和人类病原体机制的关键原因的蝙蝠冠状病毒密切相关。本综述重点介绍了新型冠状病毒病原体,包括人类和动物中的冠状病毒、其分类学分类、症状、致病性、社会影响、经济影响以及 COVID-19 的潜在治疗方法。