Fang Gang, Huang Zhennan, Wang Zhongrui
Institute of Computing Science and Technology, Guangzhou University, Guangzhou, China.
Front Genet. 2022 Jan 24;12:827522. doi: 10.3389/fgene.2021.827522. eCollection 2021.
Predicting functional outcomes after an Ischemic Stroke (IS) is highly valuable for patients and desirable for physicians. This facilitates physicians to set reasonable goals for patients and cooperate with patients and relatives effectively, and furthermore to reach common after-stroke care decisions for recovery and make exercise plans to facilitate rehabilitation. The objective of this research is to apply three current Deep Learning (DL) approaches for 6-month IS outcome predictions, using the openly accessible International Stroke Trial (IST) dataset. Furthermore, another objective of this research is to compare these DL approaches with machine learning (ML) for performing in clinical prediction. After comparing various ML methods (Deep Forest, Random Forest, Support Vector Machine, etc.) with current DL frameworks (CNN, LSTM, Resnet), the results show that DL doesn't outperform ML significantly. DL methods and reporting used for analyzing structured medical data should be developed and improved.
预测缺血性中风(IS)后的功能结局对患者非常有价值,也是医生所期望的。这有助于医生为患者设定合理的目标,与患者及其亲属有效合作,进而就中风后的康复护理达成共识并制定运动计划以促进康复。本研究的目的是使用可公开获取的国际中风试验(IST)数据集,应用三种当前的深度学习(DL)方法进行缺血性中风6个月结局预测。此外,本研究的另一个目的是将这些深度学习方法与机器学习(ML)在临床预测中的表现进行比较。在将各种机器学习方法(深度森林、随机森林、支持向量机等)与当前的深度学习框架(卷积神经网络、长短期记忆网络、残差网络)进行比较后,结果表明深度学习并没有显著优于机器学习。用于分析结构化医学数据的深度学习方法和报告有待开发和改进。