Zhong Yifan, Wang Shanshan, Di Hanqiu, Deng Zhaoxi, Liu Jianxin, Wang Haifeng
College of Animal Science, Zhejiang University, The Key Laboratory of Molecular Animal Nutrition, Ministry of Education, Hangzhou, 310058, China.
J Anim Sci Biotechnol. 2022 Apr 8;13(1):38. doi: 10.1186/s40104-022-00688-1.
Gut homeostasis is of importance to host health and imbalance of the gut usually leads to disorders or diseases for both human and animal. Postbiotics have been applied in manipulating of gut health, and utilization of postbiotics threads new lights into the host health. Compared with the application of probiotics, the characteristics such as stability and safety of postbiotics make it a potential alternative to probiotics. Studies have reported the beneficial effects of components derived from postbiotics, mainly through the mechanisms including inhibition of pathogens, strengthen gut barrier, and/or regulation of immunity of the host. In this review, we summarized the characteristics of postbiotics, main compounds of postbiotics, potential mechanisms in gut health, and their application in animal production.
肠道稳态对宿主健康至关重要，肠道失衡通常会导致人类和动物出现紊乱或疾病。后生元已被应用于调节肠道健康，后生元的利用为宿主健康带来了新的思路。与益生菌的应用相比，后生元的稳定性和安全性等特性使其成为益生菌的潜在替代品。研究报道了后生元衍生成分的有益作用，主要通过抑制病原体、增强肠道屏障和/或调节宿主免疫力等机制实现。在这篇综述中，我们总结了后生元的特性、后生元的主要化合物、在肠道健康中的潜在机制及其在动物生产中的应用。
