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纳米材料在组织工程中的应用。

Applications of nanomaterials in tissue engineering.

作者信息

Zheng Xinmin, Zhang Pan, Fu Zhenxiang, Meng Siyu, Dai Liangliang, Yang Hui

机构信息

School of Life Sciences, Northwestern Polytechnical University Xi'an 710072 P. R. China

Institute of Medical Research, Northwestern Polytechnical University Xi'an 710072 P. R. China

出版信息

RSC Adv. 2021 May 26;11(31):19041-19058. doi: 10.1039/d1ra01849c. eCollection 2021 May 24.

Abstract

Recent advancement in nanotechnology has brought prominent benefits in tissue engineering, which has been used to repair or reconstruct damaged tissues or organs and design smart drug delivery systems. With numerous applications of nanomaterials in tissue engineering, it is vital to choose appropriate nanomaterials for different tissue engineering applications because of the tissue heterogeneity. Indeed, the use of nanomaterials in tissue engineering is directly determined by the choice. In this review, we mainly introduced the use of nanomaterials in tissue engineering. First, the basic characteristics, preparation and characterization methods of the types of nanomaterials are introduced briefly, followed by a detailed description of the application and research progress of nanomaterials in tissue engineering and drug delivery. Finally, the existing challenges and prospects for future applications of nanomaterials in tissue engineering are discussed.

摘要

纳米技术的最新进展在组织工程领域带来了显著益处,组织工程已被用于修复或重建受损组织或器官,并设计智能药物递送系统。由于组织的异质性,纳米材料在组织工程中有众多应用,因此为不同的组织工程应用选择合适的纳米材料至关重要。事实上,纳米材料在组织工程中的应用直接取决于这种选择。在本综述中,我们主要介绍了纳米材料在组织工程中的应用。首先,简要介绍了各类纳米材料的基本特性、制备和表征方法,随后详细描述了纳米材料在组织工程和药物递送中的应用及研究进展。最后,讨论了纳米材料在组织工程中应用面临的现有挑战和未来应用前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f19/9033557/7e72100ba048/d1ra01849c-f1.jpg

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