Shen Zihao, Zhang Chenrui, Wang Ting, Xu Juan
Aulin College, Northeast Forestry University, Harbin 150040, China.
College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, 26 Hexing Road, Harbin 150040, China.
Polymers (Basel). 2023 Apr 23;15(9):2000. doi: 10.3390/polym15092000.
One of the most advanced, promising, and commercially viable research issues in the world of hydrogel dressing is gaining functionality to achieve improved therapeutic impact or even intelligent wound repair. In addition to the merits of ordinary hydrogel dressings, functional hydrogel dressings can adjust their chemical/physical properties to satisfy different wound types, carry out the corresponding reactions to actively create a healing environment conducive to wound repair, and can also control drug release to provide a long-lasting benefit. Although a lot of in-depth research has been conducted over the last few decades, very few studies have been properly summarized. In order to give researchers a basic blueprint for designing functional hydrogel dressings and to motivate them to develop ever-more intelligent wound dressings, we summarized the development of functional hydrogel dressings in recent years, as well as the current situation and future trends, in light of their preparation mechanisms and functional effects.
在水凝胶敷料领域,最先进、最有前景且具有商业可行性的研究课题之一是赋予其功能,以实现更好的治疗效果,甚至实现智能伤口修复。除了普通水凝胶敷料的优点外,功能性水凝胶敷料可以调节其化学/物理性质以满足不同的伤口类型,进行相应反应以主动创造有利于伤口修复的愈合环境,还可以控制药物释放以提供持久的益处。尽管在过去几十年中已经进行了大量深入研究,但很少有研究得到恰当总结。为了给研究人员提供设计功能性水凝胶敷料的基本蓝图,并激励他们开发更智能的伤口敷料,我们根据其制备机制和功能效果,总结了近年来功能性水凝胶敷料的发展情况以及现状和未来趋势。