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海洋:抗菌化合物的宝库。

Marine : A Treasure Trove of Antimicrobial Compounds.

机构信息

Key Laboratory of Geriatric Nutrition and Health, Ministry of Education of China, School of Light Industry, Beijing Technology and Business University, Beijing 100048, China.

出版信息

Mar Drugs. 2023 Apr 28;21(5):277. doi: 10.3390/md21050277.

Abstract

Secondary metabolites from marine organisms are diverse in structure and function. Marine is an important source of bioactive natural products. We reviewed the structures and antimicrobial activities of compounds isolated from different marine over the past two years (January 2021-March 2023). Ninety-eight compounds derived from species were described. The chemical diversity and antimicrobial activities of these metabolites will provide a large number of promising lead compounds for the development of antimicrobial agents.

摘要

海洋生物中的次生代谢产物结构多样,功能多样。海洋是生物活性天然产物的重要来源。我们综述了过去两年(2021 年 1 月至 2023 年 3 月)从不同海洋生物中分离得到的化合物的结构和抗菌活性。描述了 98 种来源于海洋生物的化合物。这些代谢产物的化学多样性和抗菌活性将为开发抗菌剂提供大量有前途的先导化合物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bcd/10222851/55c9b549d7a5/marinedrugs-21-00277-g001.jpg

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