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具有抗菌活性的银纳米颗粒的介导绿色合成

-Mediated Green Synthesis of Silver Nanoparticles with Antimicrobial Activity.

作者信息

Constantin Mariana, Răut Iuliana, Suica-Bunghez Raluca, Firinca Cristina, Radu Nicoleta, Gurban Ana-Maria, Preda Silviu, Alexandrescu Elvira, Doni Mihaela, Jecu Luiza

机构信息

National Institute for Research & Development in Chemistry and Petrochemistry-ICECHIM, 202 Independentei Spl., 060021 Bucharest, Romania.

Faculty of Pharmacy, Titu Maiorescu University, 16 Bd. Gh. Sincai, 040441 Bucharest, Romania.

出版信息

Materials (Basel). 2023 Jun 8;16(12):4261. doi: 10.3390/ma16124261.

Abstract

"Green chemistry" is a simple and easily reproductible method that provides nanoparticles characterized by better stability and good dispersion in an aqueous solution. Nanoparticles can be synthesized by algae, bacteria, fungi, and plant extracts. is a commonly used medicinal mushroom with distinctive biological properties, such as antibacterial, antifungal, antioxidant, anti-inflammatory, anticancer, etc. In this study, aqueous mycelial extracts of were used to reduce AgNO to form silver nanoparticles (AgNPs). The biosynthesized nanoparticles were characterized by UV-visible spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) analysis. The maximum UV absorption was obtained at 420 nm, which represents the specific surface plasmon resonance band for biosynthesized silver nanoparticles. SEM images showed particles as predominantly spherical, while FTIR spectroscopic studies illustrated the presence of functional groups that can support the reducing of ion Ag to Ag(0). XRD peaks ratified the presence of AgNPs. The antimicrobial effectiveness of synthesized nanoparticles was tested against -positive and -negative bacterial and yeasts strains. The silver nanoparticles were effective against pathogens, inhibiting their proliferation, and thus reducing the risk to the environment and to public health.

摘要

“绿色化学”是一种简单且易于重现的方法,它能制备出在水溶液中具有更好稳定性和良好分散性的纳米颗粒。纳米颗粒可通过藻类、细菌、真菌和植物提取物合成。 是一种具有独特生物学特性的常用药用蘑菇,如抗菌、抗真菌、抗氧化、抗炎、抗癌等。在本研究中, 的水菌丝体提取物被用于还原硝酸银以形成银纳米颗粒(AgNPs)。通过紫外可见光谱、扫描电子显微镜(SEM)、X射线衍射(XRD)和傅里叶变换红外光谱(FTIR)分析对生物合成的纳米颗粒进行了表征。在420nm处获得最大紫外吸收,这代表了生物合成银纳米颗粒的特定表面等离子体共振带。SEM图像显示颗粒主要为球形,而FTIR光谱研究表明存在能够支持将Ag离子还原为Ag(0)的官能团。XRD峰证实了AgNPs的存在。测试了合成纳米颗粒对革兰氏阳性和革兰氏阴性细菌及酵母菌株的抗菌效果。银纳米颗粒对病原体有效,抑制它们的增殖,从而降低对环境和公众健康的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4e6/10302571/acdd12645127/materials-16-04261-g001.jpg

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