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通过生物监测评估法国社区普通人群的铅暴露情况。

Assessment of exposure to lead of the general population in the French community through biological monitoring.

作者信息

Huel G, Boudène C, Jouan M, Lazar P

出版信息

Int Arch Occup Environ Health. 1986;58(2):131-9. doi: 10.1007/BF00380764.

DOI:10.1007/BF00380764
PMID:3744567
Abstract

The aim of the council directive of 29 March 1977 of the European Community (1) is the screening for non-work-related lead exposure levels in the general populations of European (member) countries. In France, such testing was carried out in eight metropolitan areas (having more than 500,000 inhabitants), another eight "critical" areas surrounding industrial emission sources and one area (Vosges) having a high level of lead contamination in the water. In view of the reference values (maximum 35 micrograms/dl in an individual blood sample) adopted by the directive, the situation is most serious in the area where the exposure is due to the lead contamination in the water. Individuals here run a seven times greater risk of exceeding the 35 micrograms/dl blood-lead limit relative to urban populations where the lead comes mostly from vehicle emissions into the atmosphere (i.e. 9.3% of the blood-lead values of the Vosgian sample exceed 35 micrograms/dl; 3.5% for the industrial complexes which deal with lead and 1.4% for the urban zone). While these vehicle exhausts are the subject of much current concern, in perspective, the problem of lead pipe contaminated drinking water appears to be of far greater importance.

摘要

欧洲共同体1977年3月29日理事会指令(1)的目的是对欧洲(成员国)国家普通人群中与工作无关的铅暴露水平进行筛查。在法国,此类检测在八个大城市地区(居民人数超过50万)、围绕工业排放源的另外八个“关键”地区以及一个水铅污染水平较高的地区(孚日省)进行。鉴于该指令采用的参考值(个体血样中最高35微克/分升),在因水铅污染导致暴露的地区情况最为严重。相对于铅主要来自车辆向大气排放的城市人口,这里的个体超过血铅限值35微克/分升的风险要高七倍(即孚日省样本中9.3%的血铅值超过35微克/分升;处理铅的工业园区为3.5%,市区为1.4%)。虽然目前人们对这些车辆尾气极为关注,但从长远来看,铅管污染饮用水的问题似乎更为重要。

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本文引用的文献

1
Assessment of exposure to lead of the general population in the European Community through biological monitoring.通过生物监测评估欧洲共同体一般人群的铅暴露情况。
Environ Monit Assess. 1982 Mar;2(1-2):225-31. doi: 10.1007/BF00399167.
2
[Factors of interindividual variations of blood lead levels (author's transl)].
Rev Epidemiol Sante Publique. 1981;29(2):113-24.
3
National estimates of blood lead levels: United States, 1976-1980: association with selected demographic and socioeconomic factors.美国1976 - 1980年血铅水平的全国性估计:与选定人口统计学和社会经济因素的关联
饮酒及其他生活方式因素:过量铅暴露的可避免来源。
Soz Praventivmed. 1993;38(2):43-50. doi: 10.1007/BF01318459.
4
Blood lead levels in the general population of Taiwan, Republic of China.
Int Arch Occup Environ Health. 1994;66(4):255-60. doi: 10.1007/BF00454364.
5
Exposure to lead and cadmium of children living in different areas of north-west Germany: results of biological monitoring studies 1982-1986.德国西北部不同地区儿童铅和镉暴露情况:1982 - 1986年生物监测研究结果
Int Arch Occup Environ Health. 1988;60(3):211-22. doi: 10.1007/BF00378699.
6
Influence of membrane sodium transport upon the relation between blood lead and blood pressure in a general male population.膜钠转运对普通男性人群血铅与血压关系的影响。
Environ Health Perspect. 1988 Jun;78:47-51. doi: 10.1289/ehp.887847.
7
Blood lead level distribution by age group in inhabitants of Ankara.
Biol Trace Elem Res. 1988 Dec;18:85-93. doi: 10.1007/BF02917492.
N Engl J Med. 1982 Sep 2;307(10):573-9. doi: 10.1056/NEJM198209023071001.
4
[Relationship between lead concentration in the air and blood lead levels of people living and working in the centre of a city (Frankfurt blood lead study). II. Correlations and conclusions (author's transl)].[城市中心地区居民和工作人员空气中铅浓度与血铅水平的关系(法兰克福血铅研究)。II. 相关性与结论(作者译)]
Int Arch Occup Environ Health. 1981;48(1):1-23. doi: 10.1007/BF00405927.
5
The combined effect of tobacco and alcohol consumption on the level of lead and cadmium in blood.烟草和酒精消费对血液中铅和镉水平的综合影响。
Sci Total Environ. 1985 Mar 1;41(3):207-17. doi: 10.1016/0048-9697(85)90142-1.
6
Effects of pregnancy on the inter-individual variations in blood levels of lead, cadmium and mercury.妊娠对铅、镉和汞血水平个体间差异的影响。
Biol Res Pregnancy Perinatol. 1986;7(1):37-42.