Hamblin T J, Hussain J, Akbar A N, Tang Y C, Smith J L, Jones D B
Br Med J (Clin Res Ed). 1983 Jul 9;287(6385):85-8. doi: 10.1136/bmj.287.6385.85.
In a group of patients who suffered from chronic ill health after an attack of acute infectious mononucleosis a disorder of T cell regulation was found. By means of cytochemical reactions the staining pattern associated with T suppressor cells was found in a greater percentage and that associated with T helper cells in a smaller percentage than in normal subjects. In a few patients this finding was confirmed in a functional suppressor assay. The patients were unwell for at least a year but most later made a complete recovery, which was associated with return to normal of the lymphocyte subsets.
在一组急性传染性单核细胞增多症发作后患有慢性健康问题的患者中，发现了T细胞调节紊乱。通过细胞化学反应发现，与T抑制细胞相关的染色模式在患者中的比例高于正常受试者，而与T辅助细胞相关的染色模式在患者中的比例低于正常受试者。在少数患者中，这一发现通过功能性抑制试验得到了证实。这些患者不适至少一年，但大多数后来完全康复，这与淋巴细胞亚群恢复正常有关。
