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牛疱疹病毒1型持续感染:兔模型

Persistent infection with bovine herpesvirus type 1: rabbit model.

作者信息

Rock D L, Reed D E

出版信息

Infect Immun. 1982 Jan;35(1):371-3. doi: 10.1128/iai.35.1.371-373.1982.

Abstract

Persistent infection with bovine herpesvirus type 1 (BHV-1) was established in all rabbits after conjunctival inoculation of virus. Spontaneous reactivations of BHV-1 with and without the appearance of recurrent ocular lesions were observed in persistently infected rabbits. BHV-1 was reactivated predictably and shed from all persistently infected rabbits after the administration of dexamethasone. During all reactivations, BHV-1 isolation was restricted to the inoculated eye.

摘要

在所有兔子结膜接种牛疱疹病毒1型(BHV - 1)后均建立了持续性感染。在持续感染的兔子中观察到了BHV - 1的自发再激活,有或没有复发性眼部病变出现。给予地塞米松后,BHV - 1在所有持续感染的兔子中可预测地被再激活并排出。在所有再激活过程中,BHV - 1的分离仅限于接种的眼睛。

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