传染性单核细胞增多症病例血清中的风疹特异性IgM反应性。
Rubella-specific IgM reactivity in sera from cases of infectious mononucleosis.
作者信息
Morgan-Capner P, Tedder R S, Mace J E
出版信息
J Hyg (Lond). 1983 Jun;90(3):407-13. doi: 10.1017/s0022172400029041.
Abstract
Eight sera from 125 cases of infectious mononucleosis (IM) were reactive for rubella-specific IgM in an M-antibody capture radioimmunoassay. The reactivity of individual sera varied depending upon the source of the rubella antigen used in the assay. One serum gave strongly positive results with some rubella haemagglutinating antigens but negative results with others and may have contained an IgM antibody which was capable of distinguishing between strains of rubella virus. If the diagnosis of rubella is based solely on detection in solid-phase immunoassay of rubella-specific IgM, IM should be excluded.
摘要
在一项M抗体捕获放射免疫测定中，125例传染性单核细胞增多症（IM）患者的8份血清对风疹特异性IgM呈反应性。各份血清的反应性因测定中所用风疹抗原的来源而异。一份血清对某些风疹血凝抗原有强阳性结果，但对其他抗原呈阴性结果，可能含有一种能够区分风疹病毒株的IgM抗体。如果风疹的诊断仅基于固相免疫测定中对风疹特异性IgM的检测，则应排除IM。
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