直接抗原酶免疫测定法（Herpchek）与细胞培养法用于从临床标本中检测单纯疱疹病毒的比较。
Comparison of a direct antigen enzyme immunoassay, Herpchek, with cell culture for detection of herpes simplex virus from clinical specimens.
作者信息
Verano L, Michalski F J
机构信息
Diagnostic Virology Laboratory, Corning Clinical Laboratory, Teterboro, New Jersey 07608, USA.
出版信息
J Clin Microbiol. 1995 May;33(5):1378-9. doi: 10.1128/jcm.33.5.1378-1379.1995.
Abstract
Direct enzyme immunoassay (Herpchek) was compared with culture on 21,522 specimens mainly from asymptomatic women for herpes simplex virus detection. Sensitivity and specificity were 73.8 and 97.7%, respectively. The 33% detection rate by enzyme immunoassay in 5 h increased to 43% when the enzyme immunoassay was combined with culture. Herpchek alone was not sensitive enough, but in combination with culture, maximum detection was achieved.
摘要
将直接酶免疫测定法（Herpchek）与培养法对主要来自无症状女性的21522份标本进行单纯疱疹病毒检测的结果进行了比较。敏感性和特异性分别为73.8%和97.7%。酶免疫测定法在5小时内的检出率为33%，当酶免疫测定法与培养法联合使用时，检出率提高到43%。单独使用Herpchek不够灵敏，但与培养法联合使用时，可实现最大检出率。
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