Maes B D, Ghoos Y F, Hiele M I, Rutgeerts P J
Department of Medicine, University Hospital Gasthuisberg, Leuven, Belgium.
Dig Dis Sci. 1997 Jun;42(6):1158-62. doi: 10.1023/a:1018881419010.
The underlying role of motility disorders and delayed gastric emptying in nonulcer dyspepsia is still questioned. This study aimed to determine the role of the gastric emptying rate of solids in patients with nonulcer dyspepsia. By means of breath test technology, gastric emptying results of 344 consecutive patients with nonulcer dyspepsia were compared with those of 70 normal healthy volunteers. Although gastric emptying was significantly delayed in patients with nonulcer dyspepsia compared with normal volunteers, there was a great overlap between the two groups. Using 5-95% confidence intervals of the control group in about 30% of the patients with nonulcer dyspepsia gastric emptying was delayed. No correlation was found between gastric emptying rate and age, weight, height, or sex of the subjects in both groups. These findings suggest that, apart from gastric emptying, other mechanisms are very important in the etiology of nonulcer dyspepsia.
动力障碍和胃排空延迟在非溃疡性消化不良中的潜在作用仍存在疑问。本研究旨在确定固体食物胃排空率在非溃疡性消化不良患者中的作用。通过呼气试验技术，将344例连续的非溃疡性消化不良患者的胃排空结果与70名正常健康志愿者的结果进行比较。尽管与正常志愿者相比，非溃疡性消化不良患者的胃排空明显延迟，但两组之间存在很大重叠。在约30%的非溃疡性消化不良患者中，使用对照组的5-95%置信区间发现胃排空延迟。两组受试者的胃排空率与年龄、体重、身高或性别之间均未发现相关性。这些发现表明，除胃排空外，其他机制在非溃疡性消化不良的病因中非常重要。
