阿根廷传统医学中所用植物杀锥虫活性的体外评估
In vitro evaluation of trypanocidal activity in plants used in Argentine traditional medicine.
作者信息
Sülsen V, Güida C, Coussio J, Paveto C, Muschietti L, Martino V
机构信息
Cátedra de Farmacognosia, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, (IQUIMEFA)-(UBA-CONICET), Buenos Aires, Argentina.
出版信息
Parasitol Res. 2006 Mar;98(4):370-4. doi: 10.1007/s00436-005-0060-4. Epub 2005 Dec 10.
Thirty-two organic and aqueous extracts, belonging to 12 Argentine medicinal plants were tested for their in vitro trypanocidal activity on epimastigote forms of Trypanosoma cruzi. Among the selected species, the organic extracts of Ambrosia scabra, Ambrosia tenuifolia, Baccharis spicata, Eupatorium buniifolium, Lippia integrifolia, Mulinum spinosum and Satureja parvifolia, and the aqueous extracts of E. buniifolium, L. integrifolia, M. spinosum and S. parvifolia showed trypanocidal activity with a percentage of growth inhibition higher than 70% at a concentration of 100 microg/ml.
对属于12种阿根廷药用植物的32种有机提取物和水提取物进行了体外测试，以检测它们对克氏锥虫前鞭毛体形式的杀锥虫活性。在所选物种中，糙叶豚草、细叶豚草、穗花巴戟天、短叶泽兰、全缘过江藤、多刺木莲和小叶风轮菜的有机提取物，以及短叶泽兰、全缘过江藤、多刺木莲和小叶风轮菜的水提取物表现出杀锥虫活性，在浓度为100微克/毫升时生长抑制率高于70%。
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