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生物杂交微圆柱体中由心肌细胞驱动的促动

Cardiomyocyte-Driven Actuation in Biohybrid Microcylinders.

作者信息

Yoon Jaewon, Eyster Tom W, Misra Asish C, Lahann Joerg

机构信息

Macromolecular Science and Engineering Program, University of Michigan, Ann Arbor, MI, 48109, USA.

Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.

出版信息

Adv Mater. 2015 Aug;27(30):4509-4515. doi: 10.1002/adma.201501284. Epub 2015 Jun 24.

DOI:10.1002/adma.201501284
PMID:26109501
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4844906/
Abstract

Biohybrid microcylinders are fabricated using electrohydrodynamic cojetting followed by a surface chemistry approach to maximize cell-adhesive characteristics. As proper cell alignment and mechanical stiffness are important components of bioactuator design, spatial cell selectivity and stress/strain properties of microcylinders are characterized to demonstrate their capability of response to rat cardio-myocyte contraction. These microcylinders can find applications in a host of micromechanical systems.

摘要

生物杂交微圆柱体是通过电流体动力学共喷射，然后采用表面化学方法制造的，以最大限度地提高细胞粘附特性。由于适当的细胞排列和机械刚度是生物致动器设计的重要组成部分，因此对微圆柱体的空间细胞选择性和应力/应变特性进行了表征，以证明它们对大鼠心肌细胞收缩的响应能力。这些微圆柱体可应用于许多微机械系统中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/1e511ff2f657/nihms778665f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/60551c7bf9b8/nihms778665f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/f0361a88f547/nihms778665f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/c8d41428918c/nihms778665f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/28e7af44c503/nihms778665f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/1e511ff2f657/nihms778665f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/60551c7bf9b8/nihms778665f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/f0361a88f547/nihms778665f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/c8d41428918c/nihms778665f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/28e7af44c503/nihms778665f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18d8/4844906/1e511ff2f657/nihms778665f5.jpg

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本文引用的文献

1
Cell culture on microfabricated one-dimensional polymeric structures for bio-actuator and bio-bot applications.用于生物致动器和生物机器人应用的微制造一维聚合物结构上的细胞培养。
Lab Chip. 2015 Apr 21;15(8):1879-88. doi: 10.1039/c4lc01471e.
2
Layer-by-layer assembly of 3D tissue constructs with functionalized graphene.具有功能化石墨烯的3D组织构建体的逐层组装。
Adv Funct Mater. 2014 Oct 22;24(39):6136-6144. doi: 10.1002/adfm.201401300.
3
Structurally Controlled Bio-hybrid Materials Based on Unidirectional Association of Anisotropic Microparticles with Human Endothelial Cells.基于各向异性微粒子与人体内皮细胞单向缔合的结构控制型生物杂交材料。
Adv Mater. 2009 Dec 28;21(48):4920-4925. doi: 10.1002/adma.200901971. Epub 2009 Sep 18.
4
Microfluidic devices for construction of contractile skeletal muscle microtissues.用于构建收缩性骨骼肌微组织的微流控装置。
J Biosci Bioeng. 2015 Feb;119(2):212-6. doi: 10.1016/j.jbiosc.2014.07.003. Epub 2014 Jul 30.
5
Three-dimensionally printed biological machines powered by skeletal muscle.基于骨骼肌驱动的三维打印生物机器
Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10125-30. doi: 10.1073/pnas.1401577111. Epub 2014 Jun 30.
6
Graphene nanomaterials as biocompatible and conductive scaffolds for stem cells: impact for tissue engineering and regenerative medicine.石墨烯纳米材料作为干细胞的生物相容性和导电支架：对组织工程和再生医学的影响。
J Tissue Eng Regen Med. 2015 Dec;9(12):1321-38. doi: 10.1002/term.1910. Epub 2014 Jun 11.
7
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Integrated micro/nanoengineered functional biomaterials for cell mechanics and mechanobiology: a materials perspective.用于细胞力学和力学生物学的集成微纳工程功能生物材料：材料视角
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Adv Mater. 2013 Aug 7;25(29):4028-34. doi: 10.1002/adma.201301300. Epub 2013 Jun 25.