Raoult D, Hechemy K E, Baranton G
Centre National de Reference des Rickettsioses, Centre Hospitalier Universitaire la Timone, Marseille, France.
J Clin Microbiol. 1989 Oct;27(10):2152-5. doi: 10.1128/jcm.27.10.2152-2155.1989.
We have studied the cross-reaction with Borrelia burgdorferi of sera positive for leptospirosis, syphilis, or human immunodeficiency virus by using the microimmunofluorescence test (micro-IF). The percentage of sera reactive in the micro-IF before absorption varied from 7 to 37% and was reduced to 3 to 8% after absorption with a commercial Reiter treponemal antigen. The cross-reaction of sera positive for syphilis or human immunodeficiency virus was distinguished from the homologous reaction with sera from patients with Lyme disease in the immunoblot test results. However, the cross-reaction could not always be distinguished from the homologous reaction with sera from patients with leptospirosis whose sera scored positive in the micro-IF for B. burgdorferi.
我们通过微量免疫荧光试验（微量IF）研究了钩端螺旋体病、梅毒或人类免疫缺陷病毒血清阳性患者的血清与伯氏疏螺旋体的交叉反应。吸收前微量IF中反应性血清的百分比在7%至37%之间，用商业瑞特梅毒螺旋体抗原吸收后降至3%至8%。在免疫印迹试验结果中，梅毒或人类免疫缺陷病毒血清阳性患者的血清交叉反应与莱姆病患者血清的同源反应有所区别。然而，对于钩端螺旋体病患者血清在伯氏疏螺旋体微量IF中呈阳性的情况，交叉反应并不总是能与同源反应区分开来。
