Honarmand Marieh, Farhad-Mollashahi Leila, Nakhaee Alireza, Sargolzaie Fahimeh
Oral and Dental Disease Research Center, Department of Oral Medicine, School of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran.
Dept. of Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
J Clin Exp Dent. 2017 Feb 1;9(2):e207-e210. doi: 10.4317/jced.53215. eCollection 2017 Feb.
Salivary changes in hemodialysis patients may result in various oral manifestations. This research intended to determine oral manifestations and some salivary markers in hemodialysis patients.
This cross-sectional study was conducted on 30 hemodialysis patients (the patient group) and 30 healthy individuals (the control group). Saliva urea and calcium levels and pH values of the participants were measured, and oral manifestations such as pale mucosa, xerostomia, halitosis, changes in the sense of taste, increased calculus formation, gingival bleeding, etc. were recorded in the information collection form. The data was analyzed using T-test and chi-square, and <0.05 was considered to be significant.
The mean salivary urea level and pH value in the patient group were significantly higher compared to those of the control group (<0.05), but there were no significant differences between the two groups with respect to salivary calcium. Halitosis, xerostomia, and increased calculus were the most prevalent manifestations, and gum bleeding was the least prevalent among the patients.
Advanced chronic renal insufficiency can increase salivary urea level, pH value, halitosis, xerostomia, and calculus formation, and may cause pale mucosa. Renal dialysis, biomarkers, oral manifestation, saliva.
血液透析患者的唾液变化可能导致各种口腔表现。本研究旨在确定血液透析患者的口腔表现和一些唾液标志物。
本横断面研究对30例血液透析患者（患者组）和30例健康个体（对照组）进行。测量参与者的唾液尿素、钙水平和pH值，并在信息收集表中记录口腔表现，如黏膜苍白、口干、口臭、味觉改变、牙结石形成增加、牙龈出血等。使用T检验和卡方检验分析数据，P<0.05被认为具有统计学意义。
患者组的唾液尿素水平和pH值均值显著高于对照组（P<0.05），但两组在唾液钙方面无显著差异。口臭、口干和牙结石增加是最常见的表现，牙龈出血在患者中最不常见。
晚期慢性肾功能不全可增加唾液尿素水平、pH值、口臭、口干和牙结石形成，并可能导致黏膜苍白。肾透析、生物标志物、口腔表现、唾液。
