Hernández-Mora Gabriela, Bonilla-Montoya Roberto, Barrantes-Granados Osvaldo, Esquivel-Suárez Andrea, Montero-Caballero Danilo, González-Barrientos Rocío, Fallas-Monge Zeanne, Palacios-Alfaro José David, Baldi Mario, Campos Elena, Chanto Grettel, Barquero-Calvo Elías, Chacón-Díaz Carlos, Chaves-Olarte Esteban, Guzmán Verri Caterina, Romero-Zúñiga Juan-José, Moreno Edgardo
Servicio Nacional de Salud Animal (SENASA), Ministerio de Agricultura y Ganadería, Heredia, Costa Rica.
Instituto Nacional de Aprendizaje, San José, Costa Rica.
PLoS One. 2017 Aug 9;12(8):e0182644. doi: 10.1371/journal.pone.0182644. eCollection 2017.
Brucellosis has been an endemic disease of cattle and humans in Costa Rica since the beginning of XX century. However, brucellosis in sheep, goats, pigs, water buffaloes, horses and cetaceans, has not been reported in the country. We have performed a brucellosis survey in these host mammal species, from 1999-2016. In addition, we have documented the number of human brucellosis reported cases, from 2003-2016. The brucellosis seroprevalence in goat and sheep herds was 0.98% and 0.7% respectively, with no Brucella isolation. Antibodies against Brucella were not detected in feral or domestic pigs. Likewise, brucellosis seroprevalence in horse and water buffalo farms was estimated in 6.5% and 21.7%, respectively, with no Brucella isolation. Six cetacean species showed positive reactions against Brucella antigens, and B. ceti was isolated in 70% (n = 29) of striped dolphins (Stenella coeruleoalba). A steady increase in the diagnosis of human brucellosis cases was observed. Taking into account the prevalence of brucellosis in the various host mammals of Costa Rica, different measures are recommended.
自20世纪初以来，布鲁氏菌病一直是哥斯达黎加牛和人类的一种地方病。然而，该国尚未报告绵羊、山羊、猪、水牛、马和鲸类动物感染布鲁氏菌病的情况。我们在1999年至2016年期间对这些宿主哺乳动物物种进行了布鲁氏菌病调查。此外，我们记录了2003年至2016年期间人类布鲁氏菌病的报告病例数。山羊和绵羊群中的布鲁氏菌病血清阳性率分别为0.98%和0.7%，未分离到布鲁氏菌。在野猪或家猪中未检测到抗布鲁氏菌的抗体。同样，马场和水牛场的布鲁氏菌病血清阳性率估计分别为6.5%和21.7%，未分离到布鲁氏菌。六种鲸类动物对布鲁氏菌抗原呈阳性反应，在70%（n = 29）的条纹海豚（Stenella coeruleoalba）中分离到了鲸布鲁氏菌。观察到人类布鲁氏菌病病例的诊断稳步增加。考虑到哥斯达黎加各种宿主哺乳动物中布鲁氏菌病的流行情况，建议采取不同的措施。
