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探索动物技术人员在实施3R原则中的作用:对英国大学部门的人种志调查

Exploring the Role of Animal Technologists in Implementing the 3Rs: An Ethnographic Investigation of the UK University Sector.

作者信息

Greenhough Beth, Roe Emma

机构信息

School of Geography and the Environment, Oxford University Centre for the Environment, University of Oxford, Oxford, UK.

Geography and Environment, University of Southampton, Southampton, UK.

出版信息

Sci Technol Human Values. 2018 Jul;43(4):694-722. doi: 10.1177/0162243917718066. Epub 2017 Aug 10.

Abstract

The biomedical industry relies on the skills of animal technologists (ATs) to put laboratory animal welfare into practice. This is the first study to explore how this is achieved in relation to their participation in implementing refinement and reduction, two of the three key guiding ethical principles--the "3Rs"--of what is deemed to be humane animal experimentation. The interpretative approach contributes to emerging work within the social sciences and humanities exploring care and ethics in practice. Based on qualitative analysis of participant observation within animal research facilities in UK universities, in-depth interviews with ATs, facility managers, and other stakeholders, and analysis of regulatory guidelines, we draw a contrast between the minimum required of ATs by law and how their care work not only meets but often exceeds these requirements. We outline how ATs constitute a key source of innovation and insight into the refinement of animal care and the reduction of animal use, hitherto not formally acknowledged. Exploring AT care work as an example of ethics in practice makes an original contribution to broader debates within health care and animal welfare about how technology, regulation, and behavior can foster and sustain a "culture of care".

摘要

生物医学行业依靠实验动物技术人员(ATs)的技能来将实验动物福利付诸实践。这是第一项探讨如何通过他们参与实施优化和减少措施来实现这一目标的研究,优化和减少是被视为人道动物实验的三个关键指导伦理原则——“3R”原则中的两个。这种解释性方法有助于社会科学和人文科学中正在兴起的探索实践中的关怀与伦理的工作。基于对英国大学动物研究设施内参与观察的定性分析、对实验动物技术人员、设施管理人员和其他利益相关者的深入访谈以及对监管指南的分析,我们对比了法律对实验动物技术人员的最低要求以及他们的关怀工作不仅如何满足而且常常超越这些要求。我们概述了实验动物技术人员如何构成动物护理优化和动物使用减少方面创新和见解的关键来源,而这一点迄今尚未得到正式认可。将实验动物技术人员的关怀工作作为实践伦理的一个例子来探讨,为医疗保健和动物福利领域关于技术、监管和行为如何促进和维持“关怀文化”的更广泛辩论做出了原创性贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c439/6027776/e526206969ec/10.1177_0162243917718066-fig1.jpg

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