Lister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, MD, 20894, USA.
Institute for Data Science and Informatics, University of Missouri-Columbia, Columbia, MO, 65211, USA.
BMC Infect Dis. 2020 Nov 11;20(1):825. doi: 10.1186/s12879-020-05453-1.
Light microscopy is often used for malaria diagnosis in the field. However, it is time-consuming and quality of the results depends heavily on the skill of microscopists. Automating malaria light microscopy is a promising solution, but it still remains a challenge and an active area of research. Current tools are often expensive and involve sophisticated hardware components, which makes it hard to deploy them in resource-limited areas.
We designed an Android mobile application called Malaria Screener, which makes smartphones an affordable yet effective solution for automated malaria light microscopy. The mobile app utilizes high-resolution cameras and computing power of modern smartphones to screen both thin and thick blood smear images for P. falciparum parasites. Malaria Screener combines image acquisition, smear image analysis, and result visualization in its slide screening process, and is equipped with a database to provide easy access to the acquired data.
Malaria Screener makes the screening process faster, more consistent, and less dependent on human expertise. The app is modular, allowing other research groups to integrate their methods and models for image processing and machine learning, while acquiring and analyzing their data.
在现场,显微镜检查常用于疟疾诊断。然而,这种方法既耗时,结果质量又高度依赖于检验人员的技能。自动化疟疾显微镜检查是一个很有前景的解决方案,但它仍然是一个挑战,也是一个活跃的研究领域。目前的工具通常昂贵且涉及复杂的硬件组件,这使得它们难以在资源有限的地区部署。
我们设计了一个名为 Malaria Screener 的 Android 移动应用程序,该程序使智能手机成为一种经济实惠且有效的自动化疟疾显微镜检查解决方案。该移动应用程序利用现代智能手机的高分辨率摄像头和计算能力来筛查薄血涂片和厚血涂片图像中的疟原虫寄生虫。Malaria Screener 将图像采集、涂片图像分析和结果可视化结合在其幻灯片筛查过程中,并配备了一个数据库,方便获取和分析数据。
Malaria Screener 使筛查过程更快、更一致,并且对人类专业知识的依赖程度更低。该应用程序具有模块化,可以让其他研究小组集成他们的图像处理和机器学习方法和模型,同时获取和分析他们的数据。