Ugbogu Ositadinma Chinyere, Emmanuel Okezie, Agi Grace Oka, Ibe Chibuike, Ekweogu Celestine Nwabu, Ude Victor Chibueze, Uche Miracle Ebubechi, Nnanna Rachel Oluchukwu, Ugbogu Eziuche Amadike
Department of Microbiology, Abia State University, Uturu, PMB 2000, Uturu, Abia State, Nigeria.
Department of Biochemistry, Abia State University, PMB 2000, Uturu, Abia State, Nigeria.
Heliyon. 2021 Nov 25;7(11):e08404. doi: 10.1016/j.heliyon.2021.e08404. eCollection 2021 Nov.
In traditional medicine, (clove basil) is used in the treatment of various diseases such as diabetes, cancer, inflammation, anaemia, diarrhoea, pains, and fungal and bacterial infections. The present study reviewed the phytochemicals, essential oils, and pharmacological activities of . The bioactive compounds extracted from include phytochemicals (oleanolic acid, caffeic acid, ellagic acid, epicatechin, sinapic acid, rosmarinic acid, chlorogenic acid, luteolin, apigenin, nepetoidin, xanthomicrol, nevadensin, salvigenin, gallic acid, catechin, quercetin, rutin, and kaempfero) and essential oils (camphene, β-caryophyllene, α- and β-pinene, α-humulene, sabinene, β-myrcene, limonene, 1,8-cineole, trans-β-ocimene, linalool, α- and δ-terpineol, eugenol, α-copaene, β-elemene, p-cymene, thymol, and carvacrol). Various and studies have shown that and its bioactive constituents possess pharmacological properties such as antioxidant, anti-inflammatory, anticancer, hepatoprotective, antidiabetic, antihypertensive, antidiarrhoeal, and antimicrobial properties. This review demonstrated that has a strong preventive and therapeutic effect against several diseases. The effectiveness of to ameliorate various diseases may be attributed to its antimicrobial and antioxidant properties as well as its capacity to improve the antioxidant systems. However, despite the widespread pharmacological activities of , further experiments in human clinical trial studies are needed to establish effective and safe doses for the treatment of various diseases.
在传统医学中，（丁香罗勒）被用于治疗多种疾病，如糖尿病、癌症、炎症、贫血、腹泻、疼痛以及真菌和细菌感染。本研究综述了丁香罗勒的植物化学物质、精油及其药理活性。从丁香罗勒中提取的生物活性化合物包括植物化学物质（齐墩果酸、咖啡酸、鞣花酸、表儿茶素、芥子酸、迷迭香酸、绿原酸、木犀草素、芹菜素、尼泊尔黄酮素、黄腐酚、内华达辛、 salvigenin、没食子酸、儿茶素、槲皮素、芦丁和山奈酚）和精油（莰烯、β-石竹烯、α-和β-蒎烯、α-葎草烯、桧烯、β-月桂烯、柠檬烯、1,8-桉叶素、反式-β-罗勒烯、芳樟醇、α-和δ-萜品醇、丁香酚、α-可巴烯、β-榄香烯、对伞花烃、百里香酚和香芹酚）。各种体外和体内研究表明，丁香罗勒及其生物活性成分具有抗氧化、抗炎、抗癌、保肝、抗糖尿病、抗高血压、止泻和抗菌等药理特性。本综述表明，丁香罗勒对多种疾病具有很强的预防和治疗作用。丁香罗勒改善各种疾病的有效性可能归因于其抗菌和抗氧化特性以及改善抗氧化系统的能力。然而，尽管丁香罗勒具有广泛的药理活性，但仍需要在人体临床试验研究中进行进一步实验，以确定治疗各种疾病的有效和安全剂量。
