Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Durham School of Architectural Engineering and Construction, Scott Campus, University of Nebraska-Lincoln, Omaha, NE 68182, USA.
Biosensors (Basel). 2023 Nov 7;13(11):976. doi: 10.3390/bios13110976.
The promising field of organic electronics has ushered in a new era of biosensing technology, thus offering a promising frontier for applications in both medical diagnostics and environmental monitoring. This review paper provides a comprehensive overview of organic electronics' remarkable progress and potential in biosensing applications. It explores the multifaceted aspects of organic materials and devices, thereby highlighting their unique advantages, such as flexibility, biocompatibility, and low-cost fabrication. The paper delves into the diverse range of biosensors enabled by organic electronics, including electrochemical, optical, piezoelectric, and thermal sensors, thus showcasing their versatility in detecting biomolecules, pathogens, and environmental pollutants. Furthermore, integrating organic biosensors into wearable devices and the Internet of Things (IoT) ecosystem is discussed, wherein they offer real-time, remote, and personalized monitoring solutions. The review also addresses the current challenges and future prospects of organic biosensing, thus emphasizing the potential for breakthroughs in personalized medicine, environmental sustainability, and the advancement of human health and well-being.
有机电子学这一充满前景的领域引领了生物传感技术的新纪元，为医学诊断和环境监测的应用提供了极具潜力的新前沿。本文综述全面概述了有机电子学在生物传感应用中的显著进展和潜力。文中探讨了有机材料和器件的多方面特性，突出了其独特的优势，如柔韧性、生物兼容性和低成本制造。本文深入研究了有机电子学所实现的多种生物传感器，包括电化学、光学、压电和热传感器，展示了它们在检测生物分子、病原体和环境污染物方面的多功能性。此外，还讨论了将有机生物传感器集成到可穿戴设备和物联网 (IoT) 生态系统中，为实时、远程和个性化监测提供了解决方案。本文还讨论了有机生物传感的当前挑战和未来展望，强调了在个性化医疗、环境可持续性以及人类健康和福祉的提升方面取得突破的潜力。
