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小鼠基因组的Bam重复序列属于几个超家族,其中最长的超过9千碱基对。

The Bam repeats of the mouse genome belong in several superfamilies the longest of which is over 9 kb in size.

作者信息

Meunier-Rotival M, Bernardi G

出版信息

Nucleic Acids Res. 1984 Feb 10;12(3):1593-608. doi: 10.1093/nar/12.3.1593.

DOI:10.1093/nar/12.3.1593
PMID:6322110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC318601/
Abstract

Mouse DNA contains two equally abundant, homologous subfamilies of MspI 3.6 and 5 kb repeated fragments. The first subfamily corresponds to the previously described (1) Bam 4 kb repeats, the second one to Bam repeated fragments of higher molecular weight. These subfamilies account for the vast majority of long Bam repeats and are linked with contiguous short Bam 0.5 kb repeats. A minority of these composite Bam repeats extend, on the 0.5 kb side, into R repeats. In turn, a fraction of the composite Bam/R repeats extend further, for at least 3 kb, into other repeated sequences contiguous to the R repeats. The long Bam repeats belong, therefore, in at least three superfamilies of repeats, the longest one being over 9 kb in size. Some general properties of these superfamilies are discussed.

摘要

小鼠DNA包含两个数量相等、同源的MspI 3.6 kb和5 kb重复片段亚家族。第一个亚家族对应于先前描述的(1)Bam 4 kb重复序列,第二个亚家族对应于分子量更高的Bam重复片段。这些亚家族占绝大多数长Bam重复序列,并与相邻的短Bam 0.5 kb重复序列相连。这些复合Bam重复序列中的少数在0.5 kb一侧延伸到R重复序列中。反过来,一部分复合Bam/R重复序列进一步延伸至少3 kb,进入与R重复序列相邻的其他重复序列。因此,长Bam重复序列至少属于三个重复序列超家族,其中最长的一个大小超过9 kb。讨论了这些超家族的一些一般特性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/2dd6a73f3d97/nar00321-0306-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/0c05d9bd5af1/nar00321-0303-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/32140d8e3a9f/nar00321-0303-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/0336efa25dfd/nar00321-0305-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/2dd6a73f3d97/nar00321-0306-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/0c05d9bd5af1/nar00321-0303-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/32140d8e3a9f/nar00321-0303-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/0336efa25dfd/nar00321-0305-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8c1/318601/2dd6a73f3d97/nar00321-0306-a.jpg

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本文引用的文献

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Locations of three repetitive sequence families found in BALB/c adult beta-globin clones.在BALB/c成年β-珠蛋白克隆中发现的三个重复序列家族的位置。
Nucleic Acids Res. 1981 Mar 11;9(5):1133-50. doi: 10.1093/nar/9.5.1133.
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Mouse EcoRI satellite DNA contains a sequence homologous to the long terminal repeat of the intracisternal A particle gene.
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Mol Cell Biol. 1984 Dec;4(12):2921-4. doi: 10.1128/mcb.4.12.2921-2924.1984.
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Structure of the highly repeated, long interspersed DNA family (LINE or L1Rn) of the rat.大鼠高度重复的长散在DNA家族(LINE或L1Rn)的结构
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Long interspersed repeated DNA (LINE) causes polymorphism at the rat insulin 1 locus.长散在重复DNA(LINE)导致大鼠胰岛素1基因座出现多态性。
Mol Cell Biol. 1985 Sep;5(9):2197-203. doi: 10.1128/mcb.5.9.2197-2203.1985.
6
Conservation in the 5' region of the long interspersed mouse L1 repeat: implications of comparative sequence analysis.小鼠长散在重复序列L1 5'区域的保守性:比较序列分析的意义
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J Mol Evol. 1985;22(2):117-33. doi: 10.1007/BF02101690.
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10
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