Kurtz J B, Malic A
J Clin Pathol. 1981 Dec;34(12):1392-5. doi: 10.1136/jcp.34.12.1392.
A sensitive method for detecting rubella IgM antibody, the first step of which is the attachment of the serum IgM to a solid phase, is described. Specific IgM antibody was found in all 52 people with acquired rubella in the early convalescent period, in all 38 infants with congenital rubella examined in the first seven months of life, and in 23 of 26 people immunised one to four months before testing. Twenty-four of 44 rheumatoid factor-positive sera, however, gave false-positive readings. In routine use the test was economical of both reagents and time.
本文描述了一种检测风疹IgM抗体的灵敏方法，该方法的第一步是将血清IgM附着于固相。在所有52例处于恢复期早期的获得性风疹患者、所有38例在出生后前七个月接受检查的先天性风疹婴儿以及26例在检测前一至四个月进行免疫接种的人群中，均发现了特异性IgM抗体。然而，在44例类风湿因子阳性血清中，有24例出现了假阳性结果。在常规应用中，该检测方法在试剂和时间方面都较为经济。
