来自子宫颈浸润癌的人乳头瘤病毒66型的特征分析。
Characterization of human papillomavirus type 66 from an invasive carcinoma of the uterine cervix.
作者信息
Tawheed A R, Beaudenon S, Favre M, Orth G
机构信息
Unité des Papillomavirus, Unité de l'Institut National de la Santé et de la Recherche Médicale 190, Institut Pasteur, Paris, France.
出版信息
J Clin Microbiol. 1991 Nov;29(11):2656-60. doi: 10.1128/jcm.29.11.2656-2660.1991.
Human papillomavirus (HPV) DNA sequences coexisting with HPV16 and HPV45 were cloned from an invasive cervical carcinoma. The cloned HPV was shown to be a novel type, named HPV66, and is related to HPV56 (an HPV detected in cervical cancer). After screening 160 anogenital biopsies, four specimens exhibited histological features of intraepithelial neoplasia and contained HPV66 sequences. Of these, three were found to be associated with another HPV type.
从一例浸润性宫颈癌中克隆出了与16型和45型人乳头瘤病毒（HPV）共存的HPV DNA序列。克隆出的HPV被证明是一种新型HPV，命名为HPV66，它与HPV56（一种在宫颈癌中检测到的HPV）相关。在对160份肛门生殖器活检样本进行筛查后，有4份样本表现出上皮内瘤变的组织学特征，并含有HPV66序列。其中，有3份样本被发现与另一种HPV类型有关。
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