The Chair of Medical Biology, Collegium Medicum of Nicolaus Copernicus University, Karłowicza 24, 85-092 Bydgoszcz, Poland.
Department of Orthopaedics and Musculoskeletal Traumatology, Collegium Medicum of Jagiellonian University, Os. Zlotej Jesieni 1, 31-826 Krakow, Poland.
Oxid Med Cell Longev. 2013;2013:409567. doi: 10.1155/2013/409567. Epub 2013 Dec 31.
The aim of the study was to determine the effect of single whole-body cryotherapy (WBC) session applied prior to submaximal exercise on the activity of antioxidant enzymes, the concentration of lipid peroxidation products, total oxidative status, and the level of cytokines in blood of volleyball players. The study group consisted of 18 male professional volleyball players, who were subjected to extremely cold air (-130°C) prior to exercise performed on cycloergometer. Blood samples were taken five times: before WBC, after WBC procedure, after exercise preceded by cryotherapy (WBC exercise), and before and after exercise without WBC (control exercise). The activity of catalase statistically significantly increased after control exercise. Moreover, the activity of catalase and superoxide dismutase was lower after WBC exercise than after control exercise (P < 0.001). After WBC exercise, the level of IL-6 and IL-1β was also lower (P < 0.001) than after control exercise. The obtained results may suggest that cryotherapy prior to exercise may have some antioxidant and anti-inflammatory properties. The relations between the level of studied oxidative stress and inflammatory markers may testify to the contribution of reactive oxygen species in cytokines release into the blood system in response to exercise and WBC.
本研究旨在确定单次全身冷冻疗法（WBC）在亚最大运动前应用对抗氧化酶活性、脂质过氧化产物浓度、总氧化状态以及排球运动员血液中细胞因子水平的影响。研究对象为 18 名男性职业排球运动员，他们在进行自行车测力计运动前先接触极冷的空气（-130°C）。采集了 5 次血液样本：WBC 前、WBC 后、WBC 运动后、无 WBC 运动前和无 WBC 运动后。与无 WBC 运动后相比，WBC 运动后，过氧化氢酶的活性显著增加（P < 0.001）。此外，WBC 运动后，过氧化氢酶和超氧化物歧化酶的活性低于无 WBC 运动后（P < 0.001）。WBC 运动后，IL-6 和 IL-1β 的水平也较低（P < 0.001）。这些结果表明，运动前的冷冻疗法可能具有一些抗氧化和抗炎特性。研究中氧化应激和炎症标志物水平之间的关系可能证明了活性氧物质在细胞因子释放到血液系统以响应运动和 WBC 中的作用。
