Cetinkaya Feyzullah, Atalay Ozgur Ozhan
Department of Pediatrics, Maltepe University School of Medicine, Istanbul 34843, Turkey.
Asia Pac Allergy. 2014 Jan;4(1):37-41. doi: 10.5415/apallergy.2014.4.1.37. Epub 2014 Jan 31.
Studies on the long-term effects of wheezing in infancy have particularly focused on asthma. There isn't adequate information about the effects of wheezing in the development of allergic rhinitis in later years.
In this study, children with wheezing in the first year of life were investigated in terms of allergic rhinitis after five years of age.
The study consisted of children with early-transient wheezing or persistent wheezing. The study groups were evaluated in terms of allergic rhinitis with physical examination and a questionnaire translated from International Study of Asthma and Allergies in Children (ISAAC) questionnaire after five years of age.
The study included 50 children; 23 (46%) had early-transient wheezing and 27 (54%) had persistent wheezing. The symptoms of allergic rhinitis were reported in 13 (48%) of children with persistent wheezing but in none of children with early-transient wheezing (p < 0.05). Skin prick tests showed positive results in 4.3% of children with early-transient wheezing and in 48.1% of children with persistent wheezing (p < 0.05).
Persistent wheezing, but not early transient wheezing seems to be a risk factor in the development of allergic rhinitis in children after five years of age.
关于婴儿期喘息的长期影响的研究特别关注哮喘。关于喘息对晚年变应性鼻炎发展的影响，目前尚无足够的信息。
在本研究中，对出生后第一年有喘息的儿童在五岁后进行了变应性鼻炎方面的调查。
该研究包括有早期短暂性喘息或持续性喘息的儿童。研究组在五岁后通过体格检查和一份从儿童哮喘和过敏国际研究（ISAAC）问卷翻译而来的问卷，对变应性鼻炎进行评估。
该研究纳入了50名儿童；23名（46%）有早期短暂性喘息，27名（54%）有持续性喘息。持续性喘息儿童中有13名（48%）报告有变应性鼻炎症状，而早期短暂性喘息儿童中无一例出现（p<0.05）。皮肤点刺试验显示，早期短暂性喘息儿童中有4.3%呈阳性，持续性喘息儿童中有48.1%呈阳性（p<0.05）。
持续性喘息而非早期短暂性喘息似乎是五岁后儿童变应性鼻炎发展的一个危险因素。
