替考拉宁和万古霉素纸片药敏试验的评估
Evaluation of teicoplanin and vancomycin disk susceptibility tests.
作者信息
Barry A L, Thornsberry C, Jones R N
出版信息
J Clin Microbiol. 1986 Jan;23(1):100-3. doi: 10.1128/jcm.23.1.100-103.1986.
Abstract
Disk tests with two glycopeptide antibiotics, teicoplanin and vancomycin, were evaluated, and MICs were compared with those of fusidic acid and coumermycin. For tests with 30-micrograms vancomycin disks, we recommend modification of the current zone size standards to less than or equal to 10 mm for resistant and greater than or equal 15 mm for susceptible. For teicoplanin disk tests, 30-micrograms disks are recommended, with zone size interpretive standards of less than or equal to 10 and greater than or equal 14 mm. Since no resistant clinical isolates are available at this time, susceptibility testing of either drug is rarely necessary, and zone size standards are tentative.
摘要
对两种糖肽类抗生素替考拉宁和万古霉素进行了纸片试验，并将其最低抑菌浓度（MIC）与夫西地酸和香豆霉素的MIC进行了比较。对于含30微克万古霉素纸片的试验，我们建议将当前的抑菌圈大小标准修改为：耐药时小于或等于10毫米，敏感时大于或等于15毫米。对于替考拉宁纸片试验，建议使用30微克的纸片，抑菌圈大小的解释标准为小于或等于10毫米和大于或等于14毫米。由于目前没有耐药的临床分离株，这两种药物的药敏试验很少有必要进行，抑菌圈大小标准是暂定的。
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本文引用的文献
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