Effect of Infection on Serum Lipid Profile.

BACKGROUND

Some studies suggest a significant relationship between infection and atherogenesis; but the mechanism of the relationship is almost unknown. The current study aimed at evaluating the relationship between infection and serum lipid profile.

PATIENTS AND METHODS

The current study was conducted on 2573 patients, from 2008 to 2015. The serum anti- antibody titer and serum lipid profile were assessed in the study population; data were statistically analyzed by SPSS version 16. values < 0.05 were considered significant.

RESULTS

In the current study, 66.5% of the cases were serologically positive for . Among male cases, the level of low density lipoprotein (LDL) was higher in patients with infection, compared with that of the ones without the infection ( = 0.03); although level of triglyceride (TG) was higher and the level of high density lipoprotein (HDL) was lower in the cases with infection; there was no statistically significant difference between the cases with and without infection regarding the level of HDL and TG. Among female cases, the level of TG was significantly lower in patients with infection, compared with that of the ones without the infection ( = 0.001); but there was no significant difference between the cases with and without infection regarding the level of LDL and HDL. The mean fasting blood sugar (FBS) in the cases with infection was significantly higher than that of the ones without the infection ( = 0.04).

CONCLUSION

According to the results of the current study, the levels of LDL and FBS were high among the male cases with infection. However, in females with infection the level of TG was low; hence, it seems that the atherogenicity of affected the level of blood sugar more.