Haeri Mohamadreza, Parham Mahmoud, Habibi Neda, Vafaeimanesh Jamshid
Department of Biochemistry, Qom University of Medical Sciences, Qom, Iran.
Clinical Research Development Center, Qom University of Medical Sciences, Qom, Iran.
J Lipids. 2018 Jun 3;2018:6734809. doi: 10.1155/2018/6734809. eCollection 2018.
Some studies suggest a significant relationship between infection and atherogenesis; but the mechanism of the relationship is almost unknown. The current study aimed at evaluating the relationship between infection and serum lipid profile.
The current study was conducted on 2573 patients, from 2008 to 2015. The serum anti- antibody titer and serum lipid profile were assessed in the study population; data were statistically analyzed by SPSS version 16. values < 0.05 were considered significant.
In the current study, 66.5% of the cases were serologically positive for . Among male cases, the level of low density lipoprotein (LDL) was higher in patients with infection, compared with that of the ones without the infection ( = 0.03); although level of triglyceride (TG) was higher and the level of high density lipoprotein (HDL) was lower in the cases with infection; there was no statistically significant difference between the cases with and without infection regarding the level of HDL and TG. Among female cases, the level of TG was significantly lower in patients with infection, compared with that of the ones without the infection ( = 0.001); but there was no significant difference between the cases with and without infection regarding the level of LDL and HDL. The mean fasting blood sugar (FBS) in the cases with infection was significantly higher than that of the ones without the infection ( = 0.04).
According to the results of the current study, the levels of LDL and FBS were high among the male cases with infection. However, in females with infection the level of TG was low; hence, it seems that the atherogenicity of affected the level of blood sugar more.
一些研究表明感染与动脉粥样硬化之间存在显著关联；但这种关联的机制几乎尚不清楚。本研究旨在评估感染与血清脂质谱之间的关系。
本研究于2008年至2015年对2573例患者进行。在研究人群中评估血清抗[抗体名称未给出]抗体滴度和血清脂质谱；数据采用SPSS 16版进行统计学分析。P值<0.05被认为具有显著性。
在本研究中，66.5%的病例血清学检测[感染名称未给出]呈阳性。在男性病例中，[感染名称未给出]感染患者的低密度脂蛋白（LDL）水平高于未感染患者（P = 0.03）；尽管[感染名称未给出]感染病例的甘油三酯（TG）水平较高而高密度脂蛋白（HDL）水平较低，但在HDL和TG水平方面，感染与未感染病例之间无统计学显著差异。在女性病例中，[感染名称未给出]感染患者的TG水平显著低于未感染患者（P = 0.001）；但在LDL和HDL水平方面，感染与未感染病例之间无显著差异。[感染名称未给出]感染病例的平均空腹血糖（FBS）显著高于未感染病例（P = 0.04）。
根据本研究结果，[感染名称未给出]感染的男性病例中LDL和FBS水平较高。然而，在[感染名称未给出]感染的女性中TG水平较低；因此，似乎[感染名称未给出]的致动脉粥样硬化性对血糖水平的影响更大。
