• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

合成胸部X光图像的生成与新冠肺炎检测:一种基于深度学习的方法。

Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach.

作者信息

Karbhari Yash, Basu Arpan, Geem Zong-Woo, Han Gi-Tae, Sarkar Ram

机构信息

Department of Information Technology, Pune Vidyarthi Griha's College of Engineering and Technology, Pune 411009, India.

Department of Computer Science and Engineering, Jadavpur University, Kolkata 700032, India.

出版信息

Diagnostics (Basel). 2021 May 18;11(5):895. doi: 10.3390/diagnostics11050895.

DOI:10.3390/diagnostics11050895
PMID:34069841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8157360/
Abstract

COVID-19 is a disease caused by the SARS-CoV-2 virus. The COVID-19 virus spreads when a person comes into contact with an affected individual. This is mainly through drops of saliva or nasal discharge. Most of the affected people have mild symptoms while some people develop acute respiratory distress syndrome (ARDS), which damages organs like the lungs and heart. Chest X-rays (CXRs) have been widely used to identify abnormalities that help in detecting the COVID-19 virus. They have also been used as an initial screening procedure for individuals highly suspected of being infected. However, the availability of radiographic CXRs is still scarce. This can limit the performance of deep learning (DL) based approaches for COVID-19 detection. To overcome these limitations, in this work, we developed an Auxiliary Classifier Generative Adversarial Network (ACGAN), to generate CXRs. Each generated X-ray belongs to one of the two classes COVID-19 positive or normal. To ensure the goodness of the synthetic images, we performed some experimentation on the obtained images using the latest Convolutional Neural Networks (CNNs) to detect COVID-19 in the CXRs. We fine-tuned the models and achieved more than 98% accuracy. After that, we also performed feature selection using the Harmony Search (HS) algorithm, which reduces the number of features while retaining classification accuracy. We further release a GAN-generated dataset consisting of 500 COVID-19 radiographic images.

摘要

COVID-19是一种由SARS-CoV-2病毒引起的疾病。当一个人与受感染个体接触时,COVID-19病毒就会传播。这主要是通过唾液或鼻涕飞沫传播。大多数受感染的人症状较轻,而有些人会发展为急性呼吸窘迫综合征(ARDS),这会损害肺部和心脏等器官。胸部X光(CXR)已被广泛用于识别有助于检测COVID-19病毒的异常情况。它们也被用作对高度怀疑感染的个体的初步筛查程序。然而,放射学胸部X光的可用性仍然稀缺。这可能会限制基于深度学习(DL)的COVID-19检测方法的性能。为了克服这些限制,在这项工作中,我们开发了一种辅助分类器生成对抗网络(ACGAN)来生成胸部X光。每个生成的X光属于COVID-19阳性或正常这两类中的一类。为了确保合成图像的质量,我们使用最新的卷积神经网络(CNN)对获得的图像进行了一些实验,以检测胸部X光中的COVID-19。我们对模型进行了微调,准确率达到了98%以上。之后,我们还使用和声搜索(HS)算法进行了特征选择,该算法在保留分类准确率的同时减少了特征数量。我们还发布了一个由500张COVID-19放射图像组成的GAN生成数据集。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/b49025a6ddc7/diagnostics-11-00895-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/67af1fd70218/diagnostics-11-00895-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/0939a35dfe3d/diagnostics-11-00895-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/9b5eb5be26c6/diagnostics-11-00895-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/d3f043adc41c/diagnostics-11-00895-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/49bd13b8acd8/diagnostics-11-00895-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/f81123265311/diagnostics-11-00895-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/053c850781c8/diagnostics-11-00895-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/e498d1c47a08/diagnostics-11-00895-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/b49025a6ddc7/diagnostics-11-00895-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/67af1fd70218/diagnostics-11-00895-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/0939a35dfe3d/diagnostics-11-00895-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/9b5eb5be26c6/diagnostics-11-00895-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/d3f043adc41c/diagnostics-11-00895-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/49bd13b8acd8/diagnostics-11-00895-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/f81123265311/diagnostics-11-00895-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/053c850781c8/diagnostics-11-00895-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/e498d1c47a08/diagnostics-11-00895-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2e2/8157360/b49025a6ddc7/diagnostics-11-00895-g009.jpg

相似文献

1
Generation of Synthetic Chest X-ray Images and Detection of COVID-19: A Deep Learning Based Approach.合成胸部X光图像的生成与新冠肺炎检测:一种基于深度学习的方法。
Diagnostics (Basel). 2021 May 18;11(5):895. doi: 10.3390/diagnostics11050895.
2
CovidGAN: Data Augmentation Using Auxiliary Classifier GAN for Improved Covid-19 Detection.CovidGAN:使用辅助分类器生成对抗网络进行数据增强以改进新冠病毒检测
IEEE Access. 2020 May 14;8:91916-91923. doi: 10.1109/ACCESS.2020.2994762. eCollection 2020.
3
AI-driven deep convolutional neural networks for chest X-ray pathology identification.人工智能驱动的深度卷积神经网络在胸部 X 射线病理识别中的应用。
J Xray Sci Technol. 2022;30(2):365-376. doi: 10.3233/XST-211082.
4
Deep Learning Algorithm for COVID-19 Classification Using Chest X-Ray Images.基于胸部 X 光图像的 COVID-19 分类深度学习算法。
Comput Math Methods Med. 2021 Nov 9;2021:9269173. doi: 10.1155/2021/9269173. eCollection 2021.
5
DL-CRC: Deep Learning-Based Chest Radiograph Classification for COVID-19 Detection: A Novel Approach.DL-CRC:基于深度学习的胸部X光片分类用于新冠病毒检测:一种新方法
IEEE Access. 2020 Sep 18;8:171575-171589. doi: 10.1109/ACCESS.2020.3025010. eCollection 2020.
6
Data augmentation using Generative Adversarial Networks (GANs) for GAN-based detection of Pneumonia and COVID-19 in chest X-ray images.使用生成对抗网络(GAN)进行数据增强,用于基于GAN的胸部X光图像中肺炎和新冠肺炎的检测。
Inform Med Unlocked. 2021;27:100779. doi: 10.1016/j.imu.2021.100779. Epub 2021 Nov 22.
7
Deep learning approaches for COVID-19 detection based on chest X-ray images.基于胸部X光图像的新冠肺炎检测深度学习方法
Expert Syst Appl. 2021 Feb;164:114054. doi: 10.1016/j.eswa.2020.114054. Epub 2020 Sep 28.
8
Generative adversarial network based data augmentation for CNN based detection of Covid-19.基于生成对抗网络的数据增强在基于 CNN 的新冠病毒检测中的应用。
Sci Rep. 2022 Nov 10;12(1):19186. doi: 10.1038/s41598-022-23692-x.
9
Inverted bell-curve-based ensemble of deep learning models for detection of COVID-19 from chest X-rays.基于倒钟形曲线的深度学习模型集成用于从胸部X光片中检测新冠肺炎
Neural Comput Appl. 2022 Jan 5:1-15. doi: 10.1007/s00521-021-06737-6.
10
COVID-19 detection in chest X-ray images using deep boosted hybrid learning.基于深度提升混合学习的胸部 X 射线图像 COVID-19 检测。
Comput Biol Med. 2021 Oct;137:104816. doi: 10.1016/j.compbiomed.2021.104816. Epub 2021 Aug 29.

引用本文的文献

1
Identification and exploration of novel biomarkers and potential therapeutic agents for the progression of sepsis to septic ARDS.识别和探索用于脓毒症进展为脓毒性急性呼吸窘迫综合征的新型生物标志物和潜在治疗药物。
Medicine (Baltimore). 2025 Aug 29;104(35):e44170. doi: 10.1097/MD.0000000000044170.
2
Synthetic electroretinogram signal generation using a conditional generative adversarial network.使用条件生成对抗网络生成合成视网膜电图信号
Doc Ophthalmol. 2025 Apr 16. doi: 10.1007/s10633-025-10019-0.
3
Synthetic data: how could it be used in infectious disease research?

本文引用的文献

1
A bi-stage feature selection approach for COVID-19 prediction using chest CT images.一种使用胸部CT图像进行COVID-19预测的双阶段特征选择方法。
Appl Intell (Dordr). 2021;51(12):8985-9000. doi: 10.1007/s10489-021-02292-8. Epub 2021 Apr 19.
2
OptCoNet: an optimized convolutional neural network for an automatic diagnosis of COVID-19.OptCoNet:一种用于新冠病毒疾病自动诊断的优化卷积神经网络。
Appl Intell (Dordr). 2021;51(3):1351-1366. doi: 10.1007/s10489-020-01904-z. Epub 2020 Sep 21.
3
CLIMB-COVID: continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance.
合成数据:它如何用于传染病研究?
Future Microbiol. 2024;19(17):1439-1444. doi: 10.1080/17460913.2024.2400853. Epub 2024 Sep 30.
4
Synthetic data in health care: A narrative review.医疗保健中的合成数据:一篇叙述性综述。
PLOS Digit Health. 2023 Jan 6;2(1):e0000082. doi: 10.1371/journal.pdig.0000082. eCollection 2023 Jan.
5
Unsupervised anomaly detection with generative adversarial networks in mammography.基于生成对抗网络的乳腺 X 线摄影无监督异常检测。
Sci Rep. 2023 Feb 20;13(1):2925. doi: 10.1038/s41598-023-29521-z.
6
Economics of Artificial Intelligence in Healthcare: Diagnosis vs. Treatment.医疗保健领域人工智能的经济学:诊断与治疗
Healthcare (Basel). 2022 Dec 9;10(12):2493. doi: 10.3390/healthcare10122493.
7
Application of Machine Learning and Deep Learning Techniques for COVID-19 Screening Using Radiological Imaging: A Comprehensive Review.使用放射成像的机器学习和深度学习技术在COVID-19筛查中的应用:综述
SN Comput Sci. 2023;4(1):65. doi: 10.1007/s42979-022-01464-8. Epub 2022 Nov 24.
8
Cardiovascular/Stroke Risk Stratification in Diabetic Foot Infection Patients Using Deep Learning-Based Artificial Intelligence: An Investigative Study.使用基于深度学习的人工智能对糖尿病足感染患者进行心血管/中风风险分层:一项调查研究。
J Clin Med. 2022 Nov 19;11(22):6844. doi: 10.3390/jcm11226844.
9
Deep feature selection using local search embedded social ski-driver optimization algorithm for breast cancer detection in mammograms.基于嵌入局部搜索的社会滑雪者优化算法的深度特征选择用于乳腺钼靶图像中的乳腺癌检测
Neural Comput Appl. 2023;35(7):5479-5499. doi: 10.1007/s00521-022-07895-x. Epub 2022 Nov 5.
10
Analysis of CT scan images for COVID-19 pneumonia based on a deep ensemble framework with DenseNet, Swin transformer, and RegNet.基于带有密集连接网络(DenseNet)、斯温变压器(Swin transformer)和雷吉网络(RegNet)的深度集成框架对新冠肺炎肺炎的CT扫描图像进行分析。
Front Microbiol. 2022 Sep 23;13:995323. doi: 10.3389/fmicb.2022.995323. eCollection 2022.
CLIMB-COVID:支持 SARS-CoV-2 基因组监测的去中心化测序的持续集成。
Genome Biol. 2021 Jul 1;22(1):196. doi: 10.1186/s13059-021-02395-y.
4
CovidGAN: Data Augmentation Using Auxiliary Classifier GAN for Improved Covid-19 Detection.CovidGAN:使用辅助分类器生成对抗网络进行数据增强以改进新冠病毒检测
IEEE Access. 2020 May 14;8:91916-91923. doi: 10.1109/ACCESS.2020.2994762. eCollection 2020.
5
Automated Assessment and Tracking of COVID-19 Pulmonary Disease Severity on Chest Radiographs using Convolutional Siamese Neural Networks.使用卷积暹罗神经网络对胸部X光片上的COVID-19肺部疾病严重程度进行自动评估和跟踪。
Radiol Artif Intell. 2020 Jul 22;2(4):e200079. doi: 10.1148/ryai.2020200079. eCollection 2020 Jul.
6
Towards computer-aided severity assessment via deep neural networks for geographic and opacity extent scoring of SARS-CoV-2 chest X-rays.基于深度学习的 SARS-CoV-2 胸部 X 光片地理范围和不透明度程度评分的计算机辅助严重程度评估。
Sci Rep. 2021 Apr 29;11(1):9315. doi: 10.1038/s41598-021-88538-4.
7
Detection of COVID-19 from CT scan images: A spiking neural network-based approach.从CT扫描图像中检测新型冠状病毒肺炎:一种基于脉冲神经网络的方法。
Neural Comput Appl. 2021;33(19):12591-12604. doi: 10.1007/s00521-021-05910-1. Epub 2021 Apr 16.
8
GraphCovidNet: A graph neural network based model for detecting COVID-19 from CT scans and X-rays of chest.GraphCovidNet:一种基于图神经网络的模型,用于从胸部 CT 扫描和 X 光片中检测 COVID-19。
Sci Rep. 2021 Apr 15;11(1):8304. doi: 10.1038/s41598-021-87523-1.
9
Role of Hybrid Deep Neural Networks (HDNNs), Computed Tomography, and Chest X-rays for the Detection of COVID-19.用于 COVID-19 检测的混合深度神经网络 (HDNNs)、计算机断层扫描和胸部 X 射线的作用。
Int J Environ Res Public Health. 2021 Mar 16;18(6):3056. doi: 10.3390/ijerph18063056.
10
Initial chest radiograph scores inform COVID-19 status, intensive care unit admission and need for mechanical ventilation.初始胸部X光片评分可反映新冠病毒病的病情、重症监护病房收治情况及机械通气需求。
Clin Radiol. 2021 Jun;76(6):473.e1-473.e7. doi: 10.1016/j.crad.2021.02.005. Epub 2021 Feb 18.