Suriyaprom Sureeporn, Kaewkod Thida, Promputtha Itthayakorn, Desvaux Mickaël, Tragoolpua Yingmanee
Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.
Graduate School, Chiang Mai University, Chiang Mai 50200, Thailand.
Plants (Basel). 2021 Dec 12;10(12):2736. doi: 10.3390/plants10122736.
The fruit of mulberry trees ( sp.), mulberries, are traditionally utilised as a nutritional food and provide health benefits as well as skin nourishment in Thailand. White mulberries ( L.) from Chiang Mai and Mae Hong Son provinces were evaluated for their antioxidant and antibacterial activities. The antioxidant activities as well as the total phenolic, flavonoid and anthocyanin content of the aqueous and ethanolic extracts were determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azinobis-(3-ethylbenzothiazolin-6-sulfonic acid) (ABTS) and ferric reducing antioxidant power (FRAP) assays. The aqueous extracts of mulberries exhibited the highest antioxidant activity, which was associated with a higher phenolic and anthocyanin content. In testing the potent antibacterial activity against , Typhi, , and , the mulberry extracts proved to be quite efficient, especially following water extraction. Time-kill and antibacterial adhesion assays further indicated that aqueous mulberry extracts could inhibit bacterial growth and prevent adhesions of pathogenic enteric bacteria on intestinal epithelial cells. It thus appears that mulberries can potentially be consumed as a good source of antioxidants, containing antimicrobial properties against some pathogenic bacteria which cause gastrointestinal tract infections.
桑树的果实，即桑葚，在泰国传统上被用作营养食品，具有保健功效并能滋养肌肤。对来自清迈和夜丰颂省的白桑（Morus alba L.）的抗氧化和抗菌活性进行了评估。使用2,2-二苯基-1-苦基肼（DPPH）、2,2'-联氮双（3-乙基苯并噻唑啉-6-磺酸）（ABTS）和铁还原抗氧化能力（FRAP）测定法，测定了水提取物和乙醇提取物的抗氧化活性以及总酚、黄酮和花青素含量。桑葚的水提取物表现出最高的抗氧化活性，这与较高的酚类和花青素含量有关。在测试对伤寒杆菌、副伤寒杆菌、金黄色葡萄球菌和大肠杆菌的强效抗菌活性时，桑葚提取物被证明相当有效，尤其是水提取后。时间杀菌和抗菌粘附试验进一步表明，桑葚水提取物可以抑制细菌生长并防止致病性肠道细菌粘附在肠道上皮细胞上。因此，桑葚似乎有可能作为抗氧化剂的良好来源被食用，对一些引起胃肠道感染的病原菌具有抗菌特性。
