Faculty of Pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
School of Nursing & Midwifery, Zabol University of Medical Sciences, Zabol, Iran.
J Cell Mol Med. 2024 Jun;28(11):e18383. doi: 10.1111/jcmm.18383.
Nowadays, the use of biological methods of synthesis of nanoparticles as substitutes for methods that use high energy and consumption of expensive and dangerous materials is of interest to researchers all over the world. Biological methods of synthesising metal nanoparticles are very important because they are easy, affordable, safe, environmentally friendly and able to control the size and shape of nanoparticles. One of the methods that is of interest today is the use of bacteriophages as the most abundant organisms in nature in the synthesis of metal nanoparticles. Nanomaterials biosynthesized from phages have shown various clinical applications, including antimicrobial activities, biomedical sensors, drug and gene delivery systems, cancer treatment and tissue regeneration. Therefore, the purpose of this review is to investigate the biosynthesis of metal nanoparticles with phages and their biomedical applications.
如今，研究人员对使用生物方法合成纳米粒子作为替代使用高能量和消耗昂贵、危险材料的方法很感兴趣。生物方法合成金属纳米粒子非常重要，因为它们简单、经济实惠、安全、环保，并且能够控制纳米粒子的尺寸和形状。目前受到关注的方法之一是利用噬菌体作为自然界中最丰富的生物来合成金属纳米粒子。从噬菌体生物合成的纳米材料已经显示出各种临床应用，包括抗菌活性、生物医学传感器、药物和基因传递系统、癌症治疗和组织再生。因此，本综述的目的是研究噬菌体金属纳米粒子的生物合成及其在生物医学中的应用。
