白细胞和成纤维细胞干扰素基因位于人类第9号染色体上。
Leukocyte and fibroblast interferon genes are located on human chromosome 9.
作者信息
Owerbach D, Rutter W J, Shows T B, Gray P, Goeddel D V, Lawn R M
出版信息
Proc Natl Acad Sci U S A. 1981 May;78(5):3123-7. doi: 10.1073/pnas.78.5.3123.
Abstract
At least eight leukocyte interferon genes (IFL) and the single fibroblast interferon gene (IFF) have been located on chromosome 9 in humans. In somatic cell hybrids of human and mouse cells containing a normal complement of mouse parental cell chromosomes but reduced numbers of human chromosomes, the human leukocyte and fibroblast interferon DNA sequences were present only when human chromosome 9 was also present.
摘要
至少八个白细胞干扰素基因（IFL）和单个成纤维细胞干扰素基因（IFF）已定位在人类的9号染色体上。在人和小鼠细胞的体细胞杂种中，含有正常数量的小鼠亲本细胞染色体，但人类染色体数量减少，只有当人类9号染色体也存在时，人类白细胞和成纤维细胞干扰素DNA序列才会出现。
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