Martin R, Martens U, Sticht-Groh V, Dörries R, Krüger H
Abteilung Neurologie, Universität Würzburg, Federal Republic of Germany.
J Neurol. 1988 Mar;235(4):229-33. doi: 10.1007/BF00314352.
In the cerebrospinal fluid IgG of five patients with lymphomeningoradiculitis (Bannwarth's syndrome) and radiculomyelitis studied by immunoblot technique an oligoclonal pattern was found. Most of these oligoclonal bands were specific for Borrelia burgdorferi. In patients suffering from chronic meningoradiculomyelitis, repeated CSF examination by this technique showed persistent secretion of identical IgG bands. Thus, the specific humoral immune response and the disease activity could be documented over the course of the disease.
通过免疫印迹技术研究了5例淋巴细胞性脑膜炎神经根炎（班沃思综合征）和神经根脊髓炎患者的脑脊液IgG，发现了寡克隆模式。这些寡克隆带大多对伯氏疏螺旋体具有特异性。在患有慢性脑膜神经根脊髓炎的患者中，通过该技术重复进行脑脊液检查显示相同IgG带持续分泌。因此，在疾病过程中可以记录到特异性体液免疫反应和疾病活动情况。
