人类α干扰素基因家族的染色体定位
Chromosomal location of a human alpha interferon gene family.
作者信息
Slate D L, D'Eustachio P, Pravtcheva D, Cunningham A C, Nagata S, Weissmann C, Ruddle F H
出版信息
J Exp Med. 1982 Apr 1;155(4):1019-24. doi: 10.1084/jem.155.4.1019.
Abstract
To determine the chromosomal location of the human alpha interferon genes, we scored a series of human/rodent somatic cell hybrids for the presence of DNA sequences hybridizing to an alpha 1 interferon DNA probe. The presence of human chromosome 9 in a hybrid correlated with the presence of a family of alpha interferon genes.
摘要
为了确定人类α干扰素基因的染色体定位，我们对一系列人/啮齿动物体细胞杂种进行了检测，以寻找与α1干扰素DNA探针杂交的DNA序列。杂种细胞中存在人类9号染色体与α干扰素基因家族的存在相关。
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