人类α干扰素基因家族的染色体定位
Chromosomal location of a human alpha interferon gene family.
作者信息
Slate D L, D'Eustachio P, Pravtcheva D, Cunningham A C, Nagata S, Weissmann C, Ruddle F H
出版信息
J Exp Med. 1982 Apr 1;155(4):1019-24. doi: 10.1084/jem.155.4.1019.
Abstract
To determine the chromosomal location of the human alpha interferon genes, we scored a series of human/rodent somatic cell hybrids for the presence of DNA sequences hybridizing to an alpha 1 interferon DNA probe. The presence of human chromosome 9 in a hybrid correlated with the presence of a family of alpha interferon genes.
摘要
为了确定人类α干扰素基因的染色体定位，我们对一系列人/啮齿动物体细胞杂种进行了检测，以寻找与α1干扰素DNA探针杂交的DNA序列。杂种细胞中存在人类9号染色体与α干扰素基因家族的存在相关。
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本文引用的文献
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Nature. 1980 Mar 27;284(5754):316-20. doi: 10.1038/284316a0.
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Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains.编码小鼠免疫球蛋白重链的结构基因簇的染色体定位。
J Exp Med. 1980 Jun 1;151(6):1545-50. doi: 10.1084/jem.151.6.1545.
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Further heterogeneity of human alpha interferon mRNA species.人α干扰素mRNA种类的进一步异质性。
Science. 1981 Nov 13;214(4522):803-5. doi: 10.1126/science.6170112.
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Leukocyte and fibroblast interferon genes are located on human chromosome 9.白细胞和成纤维细胞干扰素基因位于人类第9号染色体上。
Proc Natl Acad Sci U S A. 1981 May;78(5):3123-7. doi: 10.1073/pnas.78.5.3123.
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Differences between human alpha (leukocyte) and beta (fibroblast) interferons.人α（白细胞）干扰素和β（成纤维细胞）干扰素之间的差异。
Arch Virol. 1981;67(4):267-81. doi: 10.1007/BF01314831.
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